Search for dissertations about: "Soft tissue sarcoma"
Showing result 16 - 20 of 22 swedish dissertations containing the words Soft tissue sarcoma.
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16. The biological role and clinical impact of SYT-SSX fusion gene and IGF-1R in synovial sarcoma
Abstract : Synovial sarcoma, which is a highly malignant soft tissue tumour occurring mainly in young and middle-aged adults, is characterized by the translocation t(X; 18)(p 11.2; q 11.2). READ MORE
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17. Cancer risks in Swedish pesticide applicators in agriculture, forestry and gardening : a toxicological and epidemiological approach
Abstract : The aims of this thesis were (1) to study the cancer risks in Swedish pesticide applicators, which is one of the occupational groups that is most exposed to pesticides in Sweden. This could be done by utilizing a complete register kept by the Swedish Board of Agriculture which include 20,245 subjects with licenses issued between 1965 and 1976, for epidemiological studies. READ MORE
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18. Morphologic and genetic features of sarcomas : improving diagnosis and exploring biomarkers
Abstract : Sarcomas are malignant tumors of soft tissue and bone origin. They are a family of rare but diverse neoplasms which pose clinical challenges due to their heterogeneous properties. READ MORE
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19. Growth regulation in sarcomas : studies in vivo and in cell culture
Abstract : Sarcomas are malignant tumors of mesenchymal origin, and can arise in soft-tissue and in bones. It has been suggested that the abnormal growth regulation in sarcoma cells may be due to an autocrine mechanism, in which the cells are stimulated by an endogenous production of growth factors. READ MORE
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20. Exploring the therapeutic effects of p53 modulation in cancer and immune cell biology
Abstract : The tumor suppressor protein p53 is dysregulated in almost all cancer. In around 50% of cancer p53 retains wild type activity but its inactivation by the E3 ligase MDM2 in a heterodimer complex with MDMX may be amplified, leading to loss of p53 activity. READ MORE