Search for dissertations about: "Solid organ transplantation"

Showing result 6 - 10 of 10 swedish dissertations containing the words Solid organ transplantation.

  2. 6. Potentially Malignant Disorders and Oral cancer -A study on Immunosurveillance

    Author : Jenny Öhman; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oral lichen planus; Leukoplakia; Oral cancer; Immunosurveillance; Solid organ transplantation; T cells; Langerhans cells;

    Abstract : ABSTRACT The cancer immunosurveillance hypothesis postulates that the immune system can recognize cancer cell precursors and destroy those cells before a clinical manifestation occurs. During the last decades several groups have presented evidence of the influence and role of immune activation in oral squamous cell carcinoma (OSCC) patients; however, much less is known about the role of immune activation in potentially malignant oral disorders (PMOD). READ MORE

  4. 7. Clinical and Preclinical Lung Transplantation in the aspects of improving outcome

    Author : Haider Ghaidan; Thoraxkirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Lung transplantation (LTx) is an established therapeutic option for end-stage pulmonary disease. However, it remains restricted by donor lung scarcity. READ MORE

  5. 8. The discovery of antiviral compounds targeting adenovirus and herpes simplex virus : assessment of synthetic compounds and natural products

    Author : Mårten Strand; Göran Wadell; Mikael Elofsson; Ya-Fang Mei; Lieve Naesens; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; virology; antiviral; adenovirus; herpes simplex virus; small molecule; inhibitor; hsv; drug discovery; medicinsk virologi; Medical Virology; datorlingvistik; computational linguistics; mikrobiologi; Microbiology;

    Abstract : There is a need for new antiviral drugs. Especially for the treatment of adenovirus infections, since no approved anti-adenoviral drugs are available. Adenovirus infections in healthy persons are most often associated with respiratory disease, diarrhea and infections of the eye. These infections can be severe, but are most often self-limiting. READ MORE

  6. 9. Pancreatic beta-cell insulin signaling in genetic and dietary models of obesity and insulin resistance

    Author : Meike Paschen; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Type 2 Diabetes Mellitus (T2DM) is a heterogeneous metabolic disease characterized by elevated blood glucose levels that has reached pandemic proportions. Genome-wide association studies have linked T2DM to the function of the insulin-producing pancreatic βcell residing in the micro-organ islet of Langerhans. READ MORE

  7. 10. Analysis of Complement Deficiency States. With Focus on Molecular Characterization of C4 and Properdin Deficiency

    Author : Gunilla Nordin Fredrikson; Kardiovaskulär forskning - immunitet och ateroskleros; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mycology; virology; bacteriology; Complement C4; Complement; Complement Screening; Deficiency; Meningococcal Disease; Properdin; Properdin Expression; Microbiology; Sequencing; Mikrobiologi; bakteriologi; virologi; mykologi;

    Abstract : Complement deficiency is associated with an increased risk for invasive infection and immune complex disease. Screening for identification of complement-deficient patients is essential and a new ELISA-based procedure for detection of complement deficiency is described. READ MORE