Search for dissertations about: "Solid phase peptide synthesis"

Showing result 16 - 20 of 44 swedish dissertations containing the words Solid phase peptide synthesis.

  2. 16. Chemical Synthesis of Affibody Molecules for Protein Detection and Molecular Imaging

    Author : Torun Ekblad; Amelie Eriksson Karlström; Per-Åke Nygren; Harald Kolmar; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Affibody; peptide synthesis; protein detection; molecular imaging; Bioengineering; Bioteknik;

    Abstract : Proteins are essential components in most processes in living organisms. The detection and quantification of specific proteins can be used e.g. as measures of certain physiological conditions, and are therefore of great importance. READ MORE

  4. 17. Development of a new class of protecting groups for use in solid phase peptide synthesis

    Author : Amelie Karlström; James P Tam; Stockholms universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurochemistry; Neurokemi; neurokemi och neurotoxikologi; Neurochemistry and Neurotoxicology;

    Abstract : .... READ MORE

  5. 18. Development of a novel methodology for the synthesis of oligonucleo-peptide conjugates

    Author : Simone Zaramella; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Antisense; Oligonucleotide-peptide conjugates; Solid-phase synthesis; Histidine; Protecting groups.;

    Abstract : Peptide-oligonucleotide conjugates constitute a new class of antisense molecules that exhibit improved biological activity over standard oligonucleotide analogues. Currently, these oligomeric bioconjugates are prepared by either solution- or solid-phase techniques. READ MORE

  6. 19. Investigations of chemical and enzymatic functionalization of affinity proteins

    Author : Anders Myrhammar; Amelie Eriksson Karlström; Per-Åke Nygren; Christian Heinis; KTH; []
    Keywords : Affinity protein; affibody; conjugation; solid phase peptide synthesis; proteolytic stability; peptide nucleic acid PNA .; Bioteknologi; Biotechnology;

    Abstract : AbstractAffinity proteins are important reagents in research, diagnostics and therapeutic settings. The focus of this thesis has been on investigating different chemical and enzymatic strategies for engineering of affinity proteins to generate affinity reagents with improved or changed functionality. READ MORE

  7. 20. Studies towards ß-turn mimetics, synthesis of kedarosamine from threonine, and synthesis of glycopeptides from mucins and gp120

    Author : Tatjana Vuljanic; Centrum för analys och syntes; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Tn antigen; glycopeptides; glycosylation; diastereselective reduction; kedarosamine; kedarcidin chromophore; amino acids; peptide T; ß-turn mimetic; Organisk kemi; gp120; Organic chemistry;

    Abstract : The secondary structure of proteins is crucial for proper function of the protein in biological systems. Peptide T, an octapeptide from the envelope glycoprotein gp120 of the HIV virus, has previously been shown to be responsible for binding to the CD4 receptor on T helper/inducer lymphocytes. READ MORE