Search for dissertations about: "Solid tumor"
Showing result 1 - 5 of 172 swedish dissertations containing the words Solid tumor.
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1. CD40L Gene Therapy for Solid Tumors
Abstract : Adenoviral CD40L gene therapy (AdCD40L) is a strong inducer of anti-tumor immune responses via its activation of dendritic cells (DCs). Activated DCs can in turn activate T cells, which are key players in an efficient anti-tumor response.This thesis includes three papers that focus on different aspects of AdCD40L gene therapy. READ MORE
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2. Imaging the tumor microenvironment : the dynamics and modification of hypoxia
Abstract : The tumor vasculature is poor and heterogeneous which may result in inadequate oxygenation and changed energy status. In addition the balance between cell proliferation and the rate of cell death is disturbed, which results in tumor growth. READ MORE
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3. Development of a Cancer Vaccine Targeting Tumor Blood Vessels
Abstract : A treatment strategy for cancer is the suppression of tumor growth by directing an immune response to the tumor vessels, which will destroy the tissue.In this thesis we describe the development of a vaccine that targets antigens expressed around angiogenic vasculature in most solid tumors. READ MORE
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4. Monitoring of neuroendocrine tumor patients undergoing systemic therapies
Abstract : Monitoring of neuroendocrine tumor (NET) patients undergoing systemic therapies is troublesome as biomarkers capable of detecting tumor responses have been difficult to establish. Changes in the sum of target lesion diameters are used to evaluate the effects of therapy according to the response evaluation criteria in solid tumors (RECIST 1.1). READ MORE
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5. Ultrasound-assisted Interactions of Natural Killer Cells with Cancer Cells and Solid Tumors
Abstract : In this Thesis, we have developed a microtechnology-based method for culturing and visualizing high numbers of individual cells and cell-cell interactions over extended periods of time. The foundation of the device is a silicon-glass multiwell microplate (also referred as microchip) directly compatible with fluorescence microscopy. READ MORE