Search for dissertations about: "Solubility"

Showing result 1 - 5 of 440 swedish dissertations containing the word Solubility.

  1. 1. Solubility and polymorphism of molecular compounds

    Author : Sandra Gracin; Åke C. Rasmuson; David J. W. Grant; KTH; []
    Keywords : ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; Chemical engineering; solubility; prediction of solubility; UNIFAC; activity coefficients; activity of the solid phase; polymorphism; controlled crystallization; sonication.; Kemiteknik; Chemical engineering; Kemiteknik;

    Abstract : This thesis deals with the controlled crystallization of small organic molecules and is focused on solubility and polymorphism. The solubility was determined for phenylacetic acid, p-hydroxyphenylacetic acid, p-aminophenylacetic acid, p-hydroxybenzoic acid and ibuprofen in both water and in a range of organic solvents. READ MORE

  2. 2. The Chemistry of Plutonium Solubility

    Author : Hans Nilsson; Chalmers University of Technology; []
    Keywords : sorption; colloids; solubility; modeling; oxidation states; plutonium; hydrolysis; actinides;

    Abstract : When designing a repository for spent nuclear fuel it is necessary to assess the possibility that radionuclides will be transported from the repository by groundwater. A limiting factor for such transport is the solubility of any given radionuclide. READ MORE

  3. 3. Computational Analysis of Aqueous Drug Solubility – Influence of the Solid State

    Author : Carola Wassvik; Per Artursson; Anders G Holmén; Valentino J. Stella; Uppsala universitet; []
    Keywords : Pharmaceutics; intrinsic solubility; solubility prediction; drug solubility; solid state; melting point; enthalpy of melting; entropy of melting; solvation; free energy of hydration; QSPR; multivariate analysis; PCA; PLS; Galenisk farmaci;

    Abstract : Aqueous solubility is a key parameter influencing the bioavailability of drugs and drug candidates. In this thesis computational models for the prediction of aqueous drug solubility were explored. READ MORE

  4. 4. Pharmaceutical cocrystals : formation mechanisms, solubility behaviour and solid-state properties

    Author : Amjad Alhalaweh; Luleå tekniska universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cocrystal; formation; solubility; pH; dissolution; surface properties; Pharmaceutics; Pharmacy; Farmaci; Health Science; Hälsovetenskap;

    Abstract : The primary aim of pharmaceutical materials engineering is the successful formulation and process development of pharmaceutical products. The diversity of solid forms available offers attractive opportunities for tailoring material properties. READ MORE

  5. 5. Solid-liquid Phase Equilibria and Crystallization of Disubstituted Benzene Derivatives

    Author : Fredrik Nordström; Åke Rasmuson; Gerard Coquerel; KTH; []
    Keywords : ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; Salicylic acid; m-hydroxybenzoic acid; p-hydroxybenzoic acid; salicylamide; m-aminobenzoic acid; p-aminobenzoic acid; solubility; solid-liquid equilibria; thermodynamics; activity of the solid phase; ideal solubility; activity coefficient; van t Hoff enthalpy of solution; solid state; solution properties; metastable zone width; primary nucleation; nucleation kinetics; Chemical engineering; Kemiteknik;

    Abstract : The Ph.D. project compiled in this thesis has focused on the role of the solvent in solid-liquid phase equilibria and in nucleation kinetics. Six organic substances have been selected as model compounds, viz. READ MORE