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Found 3 swedish dissertations matching the above criteria.

  2. 1. Studies on the efficacy of potent anti-HIV-1 therapy on virological and immunological factors

    Author : Soo Aleman; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The aim of this thesis was to assess to which extent treated human immunodeficiency virus type I (HIV-1) infected patients with a seemingly controlled, defined as undetectable plasma HIV-1 RNA levels (< 50 copies/ml), or low-grade viral replication, exhibited pattems in virological and immunological factors which could suggest a continuation of the disease process. We have therefore analysed the kinetics of HIV-1 DNA levels (Papers I and II), the viral evolution (Paper II), the changes in Beta-chemokine levels (Paper 111) and sCD27 levels (Paper IV), and the appearance of drug resistance associated mutations (Paper V) in such patients. READ MORE

  4. 2. Autoimmune hepatitis : life, death and in-between

    Author : Åsa Danielsson Borssén; Mårten Werner; Soo Aleman; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; autoimmune hepatitis; autoimmune liver disease; hepatocellular carcinoma; surveillance; pregnancy; pregnancy outcome; cirrhosis; fibrosis; epidemiology; cause of death; medicin; Medicine;

    Abstract : Background Autoimmune hepatitis (AIH) is a chronic autoimmune liver disease that is overrepresented in women (75% of cases). Studies have described a 10-year survival after diagnosis near to that of the general population, but less is known about the long-term survival. READ MORE

  5. 3. Towards the elimination of hepatitis C : identifying the infected population, and remaining hepatitis C related risks after successful treatment

    Author : Charlotte Lybeck; Ann-Sofi Duberg; Soo Aleman; Scott Montgomery; Magnus Gottfredsson; Örebro universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HCV; HCC; epidemiology; MTCT; pregnancy; DAA; OCI;

    Abstract : Chronic Hepatitis C virus (HCV) infection can lead to liver fibrosis and cirrhosis with increased risk of hepatocellular carcinoma (HCC) and liver failure. The World Health Organisation (WHO) has set a goal to eliminate viral hepatitis as a global health threat by 2030. READ MORE