Search for dissertations about: "Sophia Thore"

Found 1 swedish dissertation containing the words Sophia Thore.

  1. 1. Regulation of Phospholipase C and Plasma Membrane Phosphatidylinositol 4,5-bisphosphate in Insulin-Secreting Cells

    Author : Sophia Thore; Anders Tengholm; Erik Gylfe; Peter Jones; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cell biology; PLC; PIP2; insulin-secreting cell; Ca2 ; evanescent wave microscopy; phosphoinositide kinase; ATP ADP ratio; Cellbiologi; Cell biology; Cellbiologi;

    Abstract : The membrane phospholipid phosphatidylinositol 4,5-bisphosphate (PIP2) is an important signaling molecule as substrate for the phospholipase C (PLC)-catalyzed formation of inositol 1,4,5-trisphosphate (IP3) and diacylglycerol, and by directly regulating e.g. ion-channels, the cytoskeleton and vesicle trafficking in various types of cells. READ MORE