Search for dissertations about: "Sophie Erhardt"

Found 1 swedish dissertation containing the words Sophie Erhardt.

2. 1. Importance of endogenous kynurenic acid in brainm catecholaminergic processes and in the pathophysiology of schizophrenia

   Author : Sophie Erhardt; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Schizophrenia; kynurenic acid; nicotine; VTA; dopamine; NMDA-receptors;

   Abstract : Kynurenic acid is a metabolite of tryptophan and the only known naturally occurring NMethylD-Aspartic acid (NMDA)-receptor antagonist (at the co-agonist glycine site) in the human brain. The aim of the present work was to investigate the physiological and pharmacological significance of endogenous kynurenic acid as well as its putative pathophysiological implications. READ MORE