Search for dissertations about: "Sox21"
Found 4 swedish dissertations containing the word Sox21.
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1. Molecular and Cellular Complexity of Glioma : Highlights on the Double-Edged-Sword of Infiltration Versus Proliferation and the Involvement of T Cells
Abstract : Glioblastoma multiforme (GBM), the most common and malignant brain tumor, is characterized by high molecular and cellular heterogeneity within and among tumors. Parameters such as invasive growth, infiltration of immune cells and endothelial proliferation contribute in a systemic manner to maintain the malignancy. READ MORE
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2. Sox proteins and neurogenesis
Abstract : The primordium of the central nervous system is specified in a process called neural induction at which point the ectoderm is subdivided into the epidermal ectoderm and the neural plate. With time the neural plate will thicken, fold and form the neural tube. READ MORE
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3. SOX in development and disease
Abstract : As stem cells are needed not only to build our bodies during development, but also to maintain tissue function during adulthood, it is of great importance to the organism to maintain their integrity. However, stem cells also pose a threat, as oncogenic mutations can transform them or their progeny to malignant cells giving rise to cancer. READ MORE
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4. Regulation of neurogenesis in the vertebrate CNS
Abstract : During development, neurons are generated from self-renewing progenitor cells in the ventricular zone of the neural tube. Proneural bHLH proteins are involved in the regulation of neurogenesis and can direct the exit of neural progenitors from the cell cycle and promote the expression of downstream differentiation markers. READ MORE