Search for dissertations about: "Spontaneous: etiology"

Showing result 1 - 5 of 23 swedish dissertations containing the words Spontaneous: etiology.

  1. 1. Spontaneous abortion : risk factors and measurement of exposures

    Author : Lena George; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Case-control study; caffeine; cotinine; environmental tobacco smoke; epidemiology; fetal karyotype; folate; maternal smoking; pregnancy; repeated spontaneous abortion; risk assessment; smoking cessation; spontaneous abortion; validation study;

    Abstract : The overall objectives of this thesis were to increase the understanding of the etiology of spontaneous abortion and repeated spontaneous abortion, and to evaluate possibilities of exposure assessment during pregnancy. Data from a Swedish population-based case-control study of spontaneous abortion, performed in Uppsala County 1996-98, formed the base for the three first studies of the thesis. READ MORE

  2. 2. Biomarkers in mid-trimester amniotic fluid in relation to gestational duration and spontaneous preterm delivery

    Author : Maria Hallingström; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; amniotic fluid; biomarkers; cytokine; damage-associated molecular pattern; gestation; gestational duration; inflammation; labor; mid-trimester; multiplex; pregnancy clock; proteins; spontaneous preterm delivery; term delivery;

    Abstract : Background: The biological mechanisms and physiological pathways of pregnancy maintenance and timing of delivery are complex and multifactorial. Pregnancy clocks, partly controlled by timing mechanisms linked to fetal development, which regulate the onset of labor has previously been described. READ MORE

  3. 3. Pregnancy related risk factors for breast cancer

    Author : Gunnar Larfors; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Breast neoplasms; epidemiology; etiology; pregnancy; hydatidiform mole; hyperemesis; abortion;

    Abstract : Pregnancies offer a life-long reduction in breast cancer risk. It has repeatedly been shown that both number of pregnancies and age at first birth affect the future breast cancer risk. The mechanisms for this protection are still not fully investigated. READ MORE

  4. 4. Models of Retinal Development and Disease

    Author : Minas Hellsand; Finn Hallböök; Emma Andersson; Department of Cell and Molecular Biology Karolinska Institutet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Developmental neurobiology; retinal organoids; retinoblastoma; MYCN; Stargardt disease; Bardet-Biedl syndrome; model systems;

    Abstract : For a model of a human disease to be valid and useful, it is important that key genotypic and phenotypic traits are shared between model system and human. The work in this thesis has been focused on generating new and characterizing spontaneous models of three genetic disorders affecting the retina: retinoblastoma, a childhood cancer with its origin in the fetal retina, Stargardt disease, a juvenile form of macular degeneration, and Bardet-Biedl syndrome, a pleiotropic ciliopathy featuring retinal degeneration. READ MORE

  5. 5. Udder cleft dermatitis in dairy cows

    Author : Lisa Ekman; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

    Abstract : Udder cleft dermatitis (UCD) is a skin condition that affects dairy cows at the fore udder attachment or between the udder halves. The lesions range from mild (eczematous skin changes) to severe (open wounds and large crusts) and may impair the welfare of the affected animals. READ MORE