Search for dissertations about: "Staffan A. Lindberg"

Found 4 swedish dissertations containing the words Staffan A. Lindberg.

  1. 1. Cell-penetrating peptides for oligonucleotide delivery : Design and uptake mechanisms

    Author : Staffan Lindberg; Ülo Langel; Arwyn Jones; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cell-penetrating peptides; gene therapy; scavenger receptors; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Abstract : The use of oligonucleotides for gene therapy has the potential to efficiently treat a plethora of diseases with minimal side effects. However, the use of oligonucleotides is hampered by the properties of these molecules, which make it essentially impossible for them to permeate the cellular membrane. READ MORE

  2. 2. The Power of Elections : Democratic Participation, Competition and Legitimacy in Africa

    Author : Staffan I Lindberg; Statsvetenskapliga institutionen; []
    Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Political and administrative sciences; methodology; Africa; democratization; democracy; Elections; institutions; Statsvetenskap; förvaltningskunskap;

    Abstract : This book is about elections and democracy in newly democratizing countries. Building on a new data set of 5,568 observations in 232 elections, it provides evidence elections have a casual impact on improving the quality of democracy in Africa in more than one way. READ MORE

  3. 3. Rational design of novel cell-penetrating peptides

    Author : Staffan Lindberg; Ülo Langel; Lena Mäler; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Abstract : Although cell-penetrating peptides (CPPs) have been an active field of research for over 20 years there are still properties such as efficiency and stability that must be improved for CPPs to reach their full potential as delivery vectors.In this thesis two peptides were designed for non-covalent oligonucleotide delivery, in an attempt to overcome two major issues hampering wider use of CPPs, namely low stability and endosomal entrapment. READ MORE

  4. 4. Promoting agency among people with severe psychiatric disability : occupation-oriented interventions in home and community settings

    Author : Maria Lindström; Margareta Lindberg; Birgitta Bernspång; Stefan Sjöström; Staffan Josephsson; Umeå universitet; []
    Keywords : Mental health; Psychotic disorders; Activities of daily living; Social participation; Recovery; Occupational therapy; Rehabilitation; Client centered; Residential facilities; Supported housing; Sheltered housing; Outcome assessment; Qualitative research; Occupational therapy; arbetsterapi;

    Abstract : In general, people with severe psychiatric disability living in sheltered or supported housing lead passive, solitary lives. Current rehabilitative approaches often neglect considering an agentic perspective of the residents in sheltered or supported housing. Furthermore, the outreach and societal contexts are often not considered. READ MORE