Search for dissertations about: "Staffan Rosenborg"

Found 1 swedish dissertation containing the words Staffan Rosenborg.

2. 1. CYP2C-dependent drug metabolism in vivo : influence of genetics and drug interactions

   Author : Staffan Rosenborg; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Cytochrome P450 enzymes (CYPs) are responsible for the metabolism of the majority of therapeutic drugs. This thesis focuses on one of the CYP subfamilies, CYP2C, especially CYP2C9 and CYP2C19, which are responsible for the metabolism of 15– 20% of all drugs. All CYP2C enzymes are polymorphic, i.e. READ MORE