Search for dissertations about: "Stathmin"

Found 4 swedish dissertations containing the word Stathmin.

  1. 1. Molecular dissection of established and proposed members of the Op18/Stathmin family of tubulin binding proteins

    Author : Kristoffer Brännström; Martin Gullberg; Fredrik Ivars; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Op18 Stathmin; Sm16; tubulin; microtubule; schistosoma mansoni; Molecular biology; Molekylärbiologi;

    Abstract : My initial aim was a functional analysis of the conserved Op18/stathmin family of microtubule-regulators, which includes the ubiquitous cytosolic Op18 protein and the neural membrane-attached RB3 and SCG10 proteins. The solved X-ray structure has shown that these proteins form a complex with tubulin -heterodimers via two imperfect helical repeats, which result in two head-to-tail aligned heterodimers in a tandem-tubulin complex. READ MORE

  2. 2. Inverted papilloma and sinonasal malignancies in Sweden

    Author : Alexandra Elliot; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Background: Sinonasal malignancies (SNMs) are rare and in Sweden they account for approximately 0,1% of all malignancies and 5% of all head and neck malignancies. Apart from sinonasal malignant melanoma (SNMM), their incidence has been reported to decrease since 1960 while the survival rates have remained rather stable during the same time-period. READ MORE

  3. 3. Cytoskeletal filament systems : assembly, regulation, and interplay in mammalian cells

    Author : Mikael E Sellin; Martin Gullberg; Jeremy Thorner; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cell research; cellforskning;

    Abstract : The cell represents the basic unit of structure and function for all life. The interior of a eukaryotic cell is organized by an extensive array of protein filaments – collectively referred to as the cytoskeleton. These filaments serve diverse essential functions, e.g. READ MORE

  4. 4. Studies on the molecular and functional properties of exosomes in the metastatic prostate cancer bone microenvironment

    Author : Ioulia Vardaki; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Prostate cancer is the most common cancer type and the second leading cancer related cause of death worldwide in men. Prostate cancer patients initially respond to standard treatment (e.g., hormonal, surgery/irradiation) but about 30% of them will develop resistance and progress to metastatic Castration Resistant Prostate Cancer (mCRPC). READ MORE