Search for dissertations about: "Sten Wingren"

Found 5 swedish dissertations containing the words Sten Wingren.

  2. 1. DNA flow cytometry of cytokeratin selected breast cancer cells as prognostic indicator

    Author : Sten Wingren; Mårten Fernö; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : DNA flow cytometry is used for the estimation of cell proliferation (S-phase fraction) and abnormalities in cellular DNA content (DNA ploidy), parameters which yield prognostic information in breast carcinomas. However, stromal, inflammatory, and residual non-neoplastic epithelial cells overlap cancer cells in the DNA histogram and complicate the calculation of DNA ploidy and S-phase fraction. READ MORE

  4. 2. Biological profiles of endocrine breast cancer

    Author : Anna Göthlin Eremo; Sten Wingren; Pia Wegman; Elisabet Tina; Karin Franzén; Agneta Jansson; Örebro universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endocrine breast cancer; tamoxifen; Foxl2; Wwox; ErbB4; HER4; gene expression; randomized patients; Biomedicin; Biomedicine;

    Abstract : .... READ MORE

  5. 3. Biological signature of HER2-positive breast cancer

    Author : Breezy Malakkaran Lindqvist; Sten Wingren; Torbjörn Nilsson; Ingrid Hedenfalk; Örebro universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HER2 breast cancer; SLC25A43; CpG island; DNA methylation; Homeobox genes; FOXO3a; FOXG1; Biomedicin; Biomedicine;

    Abstract : Human epidermal growth factor receptor 2 (HER2) overexpressing breast cancers (HER2+ breast cancer) are associated with an aggressive disease course. This thesis is focused on improving the understanding of the biological signature of HER2+ breast cancer. READ MORE

  6. 4. Studies of tamoxifen resistance in breast cancer

    Author : Pia Palmebäck Wegman; Sten Wingren; Nils Wilking; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; tamoxifen; polymorphism; metabolic enzymes; oestrogen synthesis; Oncology; Onkologi;

    Abstract : Oestrogen is one of the most important hormonal regulators and is known to play a key role in the development and growth of breast cancer. The majority of tumours have a hormone dependent growth, and this is indicated by the presence of oestrogen receptors (ERs). READ MORE

  7. 5. Biological markers in breast cancer and acute leukaemia with focus on drug resistance

    Author : Elisabet Tina; Ulf Tidefelt; Sten Wingren; Mats G. Karlsson; Jan-Ingvar Jönsson; Örebro universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; acute leukaemia; drug resistance; toposiomerase IIa; BCRP; HER2; SLC25A43; flow cytometry; real time PCR; whole genome screening; MEDICINE; MEDICIN; Oncology; Onkologi; Biomedicin; Biomedicine;

    Abstract : .... READ MORE