Search for dissertations about: "Stephanie A. Heusser"

Found 1 swedish dissertation containing the words Stephanie A. Heusser.

  1. 1. Allosteric modulation of pentameric ligand-gated ion channels by general anesthetics

    University dissertation from Stockholm : Department of Biochemistry and Biophysics, Stockholm University

    Author : Stephanie A. Heusser; Erik Lindahl; Pierre-Jean Corringer; [2018]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; biokemi; Biochemistry;

    Abstract : Pentameric ligand-gated ion channels (pLGICs) are key components of fast synaptic transmission and are targets of neuroactive drugs such as benzodiazepines, alcohol and muscle relaxants. Although early theories of general anesthesia suggested non-specific lipid interaction as the mechanism of anesthetic action, it has now become evident that they too bind to pLGICs. READ MORE