Search for dissertations about: "Stereoselective synthesis"

Showing result 1 - 5 of 55 swedish dissertations containing the words Stereoselective synthesis.

  1. 1. Stereoselective Synthesis of Amino Alcohols Applications to Natural Product Synthesis

    University dissertation from Stockholm : KTH

    Author : Staffan Torssell; KTH.; [2007]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Amino alcohol; asymmetric 1.3-dipolar cycloaddition; azomethine ylide; carbenoid; carbonyl ylide; cross-metathesis; omuralide; oxazolidine; rhodium; sphingosine; stemoamide; stereoselective synthesis; total synthesis.; NATURAL SCIENCES Chemistry Organic chemistry; NATURVETENSKAP Kemi Organisk kemi;

    Abstract : This thesis is divided into four separate parts with amino alcohols as the common feature.The first part of the thesis describes the development of an efficient three-component approach to the synthesis of α-hydroxy-β-amino esters. READ MORE

  2. 2. Asymmetric Synthesis of C-Glycosylated Amino Acids Incorporation in Collagen Glycopeptides and Evaluation in a Model for Rheumatoid Arthritis

    University dissertation from Umeå : Kemi

    Author : Tomas Gustafsson; Umeå universitet.; [2005]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Total synthesis; stereoselective synthesis; chiral glycine templates; Evan’s alkylation; asymmetric hydrogenation; alpha-amino acid synthesis; C-glycoside; rheumatoid arthritis; MHC; T cell; NATURAL SCIENCES Chemistry Organic chemistry; NATURVETENSKAP Kemi Organisk kemi;

    Abstract : This thesis describes stereoselective syntheses of four amino acids, three of which are C-glycosidic analogues of glycosylated amino acids. The overall goal of the project was to probe the interactions between MHC molecules, glycopeptide antigens and T cell receptors, that are essential for development of collagen induced arthritis. READ MORE

  3. 3. Methods for Asymmetric Olefination Reactions; Development and Application to Natural Product Synthesis

    University dissertation from Stockholm : KTH

    Author : Daniel Strand; KTH.; [2006]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Antitumor agents; Asymmetric Horner-Wadsworth-Emmons; Desymmetrization; Metal-catalyzed olefination; Mucocin; Palladium-catalyzed allylic substitution; Parallel kinetic resolution; Pyranicin; Pyragonicin; Rhenium; Stereoconvergent synthesis; Stereodivergent synthesis; Stereoselective synthesis; Tetrahydropyran; Wittig reaction; NATURAL SCIENCES Chemistry Organic chemistry; NATURVETENSKAP Kemi Organisk kemi;

    Abstract : This thesis deals with the development and application of methods for asymmetric olefinations, in particular Horner-Wadsworth-Emmons (HWE) reactions, in the synthesis of certain natural products.Relying on asymmetric HWE reactions to access key building blocks, two natu-ral products, pyranicin and pyragonicin, were synthesized from common late intermediates. READ MORE

  4. 4. Synthesis of Novel Polyhydroxyl Surfactants. Influence of the Relative Stereochemistry on Surfactant Properties

    University dissertation from Stockholm : Kemi

    Author : Kristina Neimert-Andersson; KTH.; [2003]
    Keywords : Polyhydroxyl surfactants; Sugar surfactants; Stereoselective; Synthesis; Dihydroxylation; Langmuir monolayers; Chiral discrimination;

    Abstract : This thesis deals with the synthesis and characterization ofnovel polyhydroxyl surfactants. The first part describes thesynthesis of a number of stereoisomers of a polyhydroxylsurfactant, and the second part concerns surface chemicalcharacterization. READ MORE

  5. 5. Stereoselective syntheses of semichemicals Applications in ecological chemistry

    University dissertation from Stockholm : Kemi

    Author : Ellen M. Santangelo; KTH.; [2004]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; synthesis; semiochemical; pheromone; Lepidoptera; diene; Organisk kemi; NATURAL SCIENCES Chemistry Organic chemistry; NATURVETENSKAP Kemi Organisk kemi;

    Abstract : This thesis describes the syntheses of semiochemicals and their applications in the development of control methods for pest insects. The compounds synthesized are divided into three groups: 1) Lepidoptera pheromones; 2) methyl substituted chiral pheromones and 3) aphid pheromones. READ MORE