Search for dissertations about: "Stereoselective synthesis"
Showing result 11 - 15 of 63 swedish dissertations containing the words Stereoselective synthesis.
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11. Palladium-Catalysed Couplings in Organic Synthesis : Exploring Catalyst-Presenting Strategies and Medicinal Chemistry Applications
Abstract : Palladium-catalysed coupling reactions have been embraced by synthetic chemists as one of the preferred means for smooth formation of new carbon-carbon bonds: a truly ubiquitous methodology of synthesizing complex molecules.This thesis describes the study of a series of palladium(0)-catalysed C2-arylations of a 1-cyclopentenyl ether, equipped with a chiral (S)-N-methyl-pyrrolidine auxiliary. READ MORE
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12. Serotonergic arylcyclopropylamines : stereoselective synthesis and structure-activity relationships
Abstract : .... READ MORE
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13. Bridging McMurry and Wittig in One-Pot : Olefins from Stereoselective, Reductive Couplings of Two Aldehydes via Phosphaalkenes
Abstract : The formation of C=C bonds is of great importance for fundamental and industrial synthetic organic chemistry. There are many different methodologies for the construction of C=C bonds in the literature, but currently only the McMurry reaction allows the reductive coupling of two carbonyl compounds to form alkenes. READ MORE
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14. Enantio- and Regioselective Iridium-Catalyzed Hydrogenation of Olefins : From Development to Total Synthesis
Abstract : The work presented in this thesis concerns the iridium-catalyzed asymmetric hydrogenation of cyclic olefins and allylic alcohols for the preparation of useful chiral intermediates with various substitution patterns. The strategy provides stereocontrol for both non-functionalized as well as functionalized substrates and aims to be implemented in the stereoselective preparation of chiral building blocks having more than one stereocenter. READ MORE
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15. Synthetic analogs of sialyl Lewis x
Abstract : The sialyl Lewis x (SLex) tetrasaccharide is the smallest recognizable ligand for selectins. The selectins constitute a vital part of the inflammatory cascade for recruitment of leukocytes to a site of tissue damage or microbial infection. READ MORE