Search for dissertations about: "Steven Singer"

Found 2 swedish dissertations containing the words Steven Singer.

  2. 1. The interplay between Giardia intestinalis and host intestinal epithelial cells : A tale of immune activation and suppression

    Author : Jana Grüttner; Staffan Svärd; Mikael E. Sellin; Steven Singer; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Giardia; diarrhea; RNAseq; proteomics; small intestinal epithelial cells; enteroids; organoids; protozoan; differentiation; immune response; host-parasite interaction; swimming; Biologi med inriktning mot mikrobiologi; Biology with specialization in Microbiology;

    Abstract : Giardia intestinalis is a non-invasive, protozoan parasite causing the diarrheal disease giardiasis in a variety of mammals, including humans. The parasite has two main life cycle stages; disease-causing trophozoites and infectious cysts. Trophozoites colonize the host’s upper small intestine by attaching to intestinal epithelial cells (IECs). G. READ MORE

  4. 2. Studies of Giardia-host interactions: role of cysteine-rich surface proteins

    Author : Dimitra Peirasmaki; Staffan Svärd; Steven Singer; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Giardia; intestinal parasite; parasite infection; host-parasite interaction; virulence factors; HCMPs; cysteine-rich proteins; secretome; proteome;

    Abstract : Giardia intestinalis is a eukaryotic parasite that colonizes the small intestine of humans and animals causing the diarrheal disease known as giardiasis. This parasite is not invasive and does not internalize into host cells but it rather attaches to the brush border surface of the small intestine disrupting the epithelial barrier. READ MORE