Search for dissertations about: "Stina Söderlund"

Found 2 swedish dissertations containing the words Stina Söderlund.

  2. 1. Clinical and Immunological Studies in Chronic Myeloid Leukaemia

    Author : Stina Söderlund; Ulla Olsson-Strömberg; Angelica Loskog; Satu Mustjoki; Dragana Milojkovic; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; chronic myeloid leukaemia; accelerated phase; blast crisis; tyrosine kinase inhibitor; immunology; myeloid-derived suppressor cells; cytokines; proteomics; TKI discontinuation; population-based;

    Abstract : Chronic myeloid leukaemia (CML) is characterised by the constitutively active tyrosine kinase BCR-ABL. Standard treatment with tyrosine kinase inhibitors (TKI) in the chronic phase (CP) of CML conveys excellent long-term prognosis but is associated with side effects and costs. READ MORE

  4. 2. Clinical and Genetic studies in Chronic Myeloid Leukaemia

    Author : Hjalmar Flygt; Ulla Olsson Strömberg; Stina Söderlund; Lucia Cavelier; Jane Apperley; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Haematology; Chronic Myeloid Leukemia; Medicinsk vetenskap; Medical Science;

    Abstract : This thesis explores strategies to enhance deep molecular response (DMR) rates and treatment-free remission (TFR) eligibility in chronic myeloid leukaemia (CML), investigates factors linked to treatment milestone failures, describes tyrosine kinase inhibitor (TKI) discontinuation outcomes in a population-based cohort, and examines TFR probabilities after a second TKI discontinuation. In paper I we examined data from the Swedish CML registry on 128 CML patients in chronic phase with a reported TKI discontinuation of ≥1 month due to DMR. READ MORE