Search for dissertations about: "Streptococcus pyogenes GAS"

Showing result 1 - 5 of 24 swedish dissertations containing the words Streptococcus pyogenes GAS.

2. 1. Studies on secreted cysteine proteases of Streptococcus pyogenes : IdeS and SpeB

   Author : Reine Vindebro; Ulrich von Pawel-Rammingen; Wolfgang Knecht; Umeå universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Streptococcus pyogenes; Group A Streptococci; GAS; virulence factor; IdeS; SpeB; cysteine protease; protease inhibitor; IgG; immune evasion; molekylär bioteknik inst f molekylärbiologi ; molecular biotechnology dept of molecular biology ;

   Abstract : The pathogen Streptococcus pyogenes is a significant cause of human morbidity and mortality. Most of the work in this thesis is focused on streptococcal virulence factor IdeS, but the thesis also features work on SpeB, another streptococcal virulence factor. READ MORE

4. 2. Quantifying Phagocytosis – studies on the antibody response during invasive streptococcal infections

   Author : Therese de Neergaard; Infektionsmedicin; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Phagocytosis; Hill equation; Streptococcus pyogenes GAS ; Streptococcus dysgalactiae; Antibodies; invasive infection; Phagocytosis; Hill equation; Streptococcus pyogenes; Group A Streptococcus; Streptococcus dysgalactiae; Antibodies; Invasive infection;

   Abstract : The interaction between our immune system and pathogens encompasses a complex spectrum from symbiosis to potentially life-threatening diseases. Throughout evolution, our immune system has evolved numerous strategies such as phagocytosis to combat infections and protect us from diseases. READ MORE

5. 3. Mechanisms of phagocytosis resistance in Streptococcus pyogenes

   Author : Heike Kotarsky; Lund Pediatrik; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microbiology; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi; fibrinogen; FHL-1; Factor H; M protein; Streptococcus pyogenes; phagocytosis;

   Abstract : A distinguishing feature of Streptococcus pyogenes (GAS) is their ability to resist phagocytosis in whole human blood in the absence of type-specific antibodies, a property that is dependent on the expression of the surface associated M proteins. A common characteristic of M proteins is their interaction with a variety of host proteins including the complement regulatory protein factor H (FH) and fibrinogen that plays a key role in coagulation. READ MORE

6. 4. Superantigens in group A streptococcus : gene diversity and humoral immune response

   Author : Linda Maripuu; Mari Norgren; Susan Hollingshead; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Group A streptococcus; Streptococcus pyogenes; superantigen SAg ; SAg-gene profile; M-protein; emm-genotype; biomedicinsk laboratorievetenskap; biomedical laboratory science;

   Abstract : Group A streptococcus (GAS) is a strictly human pathogen that causes infections ranging from asymptomatic carriage to the highly lethal streptococcal toxic shock syndrome (STSS). GAS are classified according to the sequence of the variable 5’ end of the emm-gene that encodes the surface associated M-protein. READ MORE

7. 5. Severe Streptococcus pyogenes disease in Europe; epidemiology and clinical manifestations

   Author : Bogdan Luca; Avdelningen för medicinsk mikrobiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Streptococcus pyogenes; streptococcal toxic shock syndrome; necrotising fasciitis; emm-type; invasive GAS disease; superantigen;

   Abstract : Streptococcus pyogenes, gives rise from mild skin infections and pharyngitis, to life threatening infections like bacteraemia, cellulitis, puerperal sepsis, meningitis, pneumonia, necrotizing fasciitis (NF), and streptococcal toxic-like shock syndrome (STSS), or nonsuppurative sequelae, rheumatic fever and glomerulonephritis. In 2002, the first multinational network for invasive GAS disease surveillance was initiated by the EU-funded Strep-EURO project. READ MORE