Search for dissertations about: "Streptolysin O"
Found 5 swedish dissertations containing the words Streptolysin O.
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1. Immunoglobulin-binding bacterial surface proteins; biomedical tools and virulence factors
University dissertation from Lund University, Dept. of Cell and Molecular Biology, P.O. Box 94, S-221 00 Lund, SwedenAbstract : Popular Abstract in Swedish Populärvetenskaplig sammanfattning Antikroppar, även kallade immunoglobuliner, är proteiner som utgör en viktig del i vårt försvar mot infektioner genom att de kan binda och neutralisera ämnen som uppfattas som främmande, t ex bakterier, virus eller produkter som produceras av dessa organismer. Antikropparna består av en antigen-bindande variabel del som binder till det kroppsfrämmande ämnet och en konstant del som samverkar med andra komponenter i immunförsvaret. READ MORE
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2. Interactions between Streptococcus pyogenes and the human immune defence
University dissertation from Department of Clinical Sciences, Lund UniversityAbstract : Streptococcus pyogenes is an important human pathogen frequently colonizing the throat and skin of humans. To facilitate colonization and spread and to avoid the host immune defence, streptococci are endowed with a variety of virulence factors, two of which are investigated in this thesis namely streptolysin O (SLO) and M protein. READ MORE
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3. Regulation of inflammasomes by host- and pathogen-derived factors
University dissertation from Lund University, Faculty of MedicineAbstract : The term inflammasome was first coined in 2002 and describes an intracellular multiprotein complex mediating inflammation by inducing the release of pro-inflammatory cytokines (IL-1β and IL-18) and a lytic form of cell death called pyroptosis. Since then, an impressive amount of research has revealed many details about the mechanisms of inflammasome activation as well as the functional relevance of inflammasome activation in different contexts. READ MORE
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4. Influence of MHC class 1:peptide interaction on antigen presentation in normal and malignant cells
University dissertation from Stockholm : Karolinska Institutet, falseAbstract : INFLUENCE OF MHC CLASS l:PEPTIDE INTERACTION ON ANTIGEN PRESENTATION IN NORMAL AND MALIGNANT CELLS Qian-Jin Zhang Doctoral dissertation from the Microbiology and Tumor Biology Center, Karolinska Institute, Stockholm, SwedenThe presentation of MHC class I:peptide complexes in normal andmalignant cells was studied. An HLA A11 binding motif was defined bycomparing synthetic peptide analogues of a known cytotoxic T Iymphocyte(CTL) target epitope for induction of surface A11 expression and triggering ofcytotoxic activity. READ MORE
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5. Metabolic signals in the regulation of insulin release
University dissertation from Stockholm : Karolinska Institutet, falseAbstract : In the present thesis, an attempt was made to elucidate the role of some of the glucose-induced intracellular metabolic effector signals in insulin secretion and to develop new applications that will enable further investigations of oscillatory signalling and secretion from pancreatic ß-cells. The sequence of early metabolic and ionic events was examined in clonal pancreatic insulin secreting cells (HIT) in response to glucose stimulation. READ MORE
