Search for dissertations about: "Stress granules"

Showing result 1 - 5 of 26 swedish dissertations containing the words Stress granules.

  2. 1. Functional roles of protein phase separated assemblies in cellular stress response and proteinopathies

    Author : Michelle Lindström; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; phase separation; LLPS; stress granules; Lsm7; FUS; Ccr4;

    Abstract : For a long time, pertinent biological conundrums, such as the organization and compartmentalization of the cytoplasm and nucleoplasm, perplexed the scientific community. The organization of the complex biochemistry in an accurate space and time manner could not be explained without the enclosure of a membrane. READ MORE

  4. 2. Imaging the molecular pathways of neurodegeneration : New pathologies of SCA7

    Author : Frida Niss; Anna-Lena Ström; Einar Hallberg; Georg Auberger; Stockholms universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurodegeneration; SCA7; Polyglutamine diseases; RNA binding proteins; Aggregation; Stress granules; Chromatin organization; Quantitative image analysis; Nuclear envelope; Nuclear pore complex; Nucleocytoplasmic transport; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Abstract : Spinocerebellar Ataxia type 7 (SCA7) is a genetic neurodegenerative disease with lethal outcome that affects the cerebellum and retina of patients. This thesis focuses on characterising molecular pathological pathways that cause toxicity and cell death in SCA7. READ MORE

  5. 3. Stress & Granules : regulation of Cauliflower mosaic virus disease in Arabidopsis thaliana

    Author : Gesa Hoffmann; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

    Abstract : Viruses exist in intimate relationships with the organisms they are infecting and are just as dependent on compatibility with their host’s cellular components as they are on subverting them. During any virus infection, the cells are flooded with foreign nucleic acids (DNA and/or RNA) and have learned to recognize, disarm, or eliminate them. READ MORE

  6. 4. Post-transcriptional regulation after stress in Schizosaccharomyces pombe

    Author : Daniel Nilsson; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Post transcriptional regulation;

    Abstract : Post transcriptional regulation is part of the gene expression control and is important for many cellular processes. It influences how mRNAs are selected for translation, degradation or storage. In this thesis, I describe some of the known mechanisms for transcriptional regulation in S. READ MORE

  7. 5. Degradation and sequestration : cellular strategies to counteract proteotoxic stress

    Author : Shanshan Xu; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Maintenance of proteome homeostasis (proteostasis) is essential to preserve cellular function in response to intrinsic and extrinsic stress conditions. This is regulated by the proteostasis network, which is comprised of machineries for protein synthesis, folding, sequestering, and degradation. READ MORE