Search for dissertations about: "Stromal Cells"

Showing result 1 - 5 of 196 swedish dissertations containing the words Stromal Cells.

  1. 1. MESENCHYMAL STEM- AND STROMAL CELLS IN BONE MARROW AND OSTEOSARCOMA

    Author : Jan Claas Brune; Stamcellscentrum (SCC); []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mesenchymal stem cells; stromal cells; bone marrow stem cells; tumour stroma; stroma-directed anti-tumour therapy; osteosarcoma;

    Abstract : Primary mesenchymal stem cells (MSC) play a central role in bone marrow (BM) and during haematopoiesis. Yet, the exact phenotype and spatial distribution of primary MSC in the human BM are unknown. Their cultured progeny are promising candidates for clinical applications. READ MORE

  2. 2. Generation of Dopaminergic Neurons from Human Embryonic Stem Cells

    Author : Tandis Vazin; Joakim Lundeberg; Ernest Arenas; KTH; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Human; dopaminergic; embryonic stem cells; differentiation; stromal cells; PA6 cells; dopamine; neurons; Neuroscience; Neurovetenskap; Neurobiology; Neurobiologi; Molecular neurobiology; Molekylär neurobiologi;

    Abstract : Since the first successful derivation of human embryonic stem cells (hESC), rapid progress has been attained in the development of strategies in differentiation of these cells into various neural lineages, with the fundamental objective of using these cells for replacement and repair of damaged neuronal circuits in the central nervous system (CNS). Of particular interest are midbrain dopaminergic (mDA) neurons, which play a central role in regulation of voluntary movement. READ MORE

  3. 3. Mesenchymal stromal cells in lung tissue

    Author : Sara Rolandsson Enes; Lungbiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mesenchymal stromal cells; lung transplantation; bronchiolitis obliterans syndrome; obliterative bronchiolitis; extracellular matrix;

    Abstract : Mesenchymal stromal cells (MSC) are multipotent cells with immunomodulatory and regenerative properties. During recent years, the interest in using MSC for clinical approaches for various diseases have increased. READ MORE

  4. 4. Regulatory Proteins in Progenitors and Differentiated Cells of the Human Prostate

    Author : Jens Ceder; Malmö (Abrahamsson) Urologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mesenchymal stem cells; somatostatin; transit amplifying cells; cell differentiation; adult stem cells; Prostate gland; prostatic benign hyperplasia; neuroendocrine cells; prostate cancer;

    Abstract : Prostate cancer (PC) develops from an androgen-dependent tissue that contains androgen receptors in both the stromal and glandular compartments. Surgical removal of the prostate may cure the patient, but if metastatic spread has occurred, androgen suppression therapy is the standard treatment. READ MORE

  5. 5. Immune cells in pregnant uterine mucosa : functional properties, cellular composition and tissue organization

    Author : Lucia Mincheva-Nilsson; Sten Hammarström; Rolf Kiessling; Umeå universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; immunologically privileged site; TCR γδ cells; CD56 cells; large granular lymphocytes; immunosuppression; cytokine; interleukin; lymphoid cell cluster; intraepithelial lymphocytes; glandular epithelium; immuno electron microscopy; pregnancy; decidua; lactoferrin; lactoferrin receptor; colostrum;

    Abstract : The pregnant uterus mucosa - decidua - is an "immunologically privileged" site. A semiallogeneic embryo is allowed to survive, develop, and grow while the same tissue implanted outside the uterus will be rejected. The decidua basalis, which participates in the placenta formation, is a tissue rich in lymphoid cells. READ MORE