Search for dissertations about: "Structural biochemistry"

Showing result 11 - 15 of 406 swedish dissertations containing the words Structural biochemistry.

  2. 11. Structural Studies on PP2A and Methods in Protein Production

    Author : Auður Magnúsdóttir; Pär Nordlund; Herman Van Tilbeurgh; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; PP2A; PTPA; B56γ; Protein Production; Structural biology; Strukturbiologi; biokemi; Biochemistry;

    Abstract : PP2A is a major phosphatase in the cell that participates in multiple cell signaling pathways. It is a heterotrimer of a core dimer and variable regulatory subunits. Details of its structure, function and regulation are slowly emerging. Here, the structure of two regulators of PP2A are de-scribed; PTPA and B56γ. READ MORE

  4. 12. Membrane Protein Tailoring and Structural Studies of Leukotriene C4 Synthase

    Author : Daniel Martinez Molina; Pär Nordlund; Robert M. Stroud; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; membrane proteins; random mutagenesis; detergent screening; Leukotriene C₄ synthase; IMAC; Structural biology; Strukturbiologi; Biochemistry; biokemi;

    Abstract : Despite a dramatic increase in the number of proteins that have been structurally characterized in recent years, there are still less than 200 unique structures of membrane proteins known today. This is only 1% of the total number of unique protein structures found in structural databases worldwide. READ MORE

  5. 13. Structural studies of R2 and R2–like proteins with a heterodinuclear Mn/Fe cofactor and enzymes involved in Mycobacterium tuberculosis lipid metabolism

    Author : Charlotta Selina Andersson; Martin Högbom; Brian Fox; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; biokemi;

    Abstract : Tuberculosis is a notorious disease responsible for the deaths of 1.4 million people worldwide. A third of the world's population is infected with Mycobacterium tuberculosis, the bacterium causing the disease. READ MORE

  6. 14. Establishing the molecular mechanism of sodium/proton exchangers

    Author : Povilas Uzdavinys; David Drew; Peter Brzezinski; M.D. Daniel Fuster; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; membrane protein; secondary active transporters; sodium proton exchangers; proton transport; structure; energetics; Biochemistry; biokemi;

    Abstract : Sodium/proton exchangers are ubiquitous secondary active transporters that can be found in all kingdoms of life. These proteins facilitate the transport of protons in exchange for sodium ions to help regulate internal pH, sodium levels, and cell volume. READ MORE

  7. 15. Role of respiratory supercomplexes : Electronic connection between complexes III and IV

    Author : Agnes Moe; Peter Brzezinski; James A. Letts; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; electron transfer; cytochrome c oxidase; cytochrome bc1; respiratory supercomplex; bioenergetics; membrane protein; biokemi; Biochemistry;

    Abstract : In the final step of cellular respiration, electrons are transferred through the respiratory chain to reduce molecular oxygen to water. The energy released in this chain is used to maintain a proton electrochemical gradient across the cell membrane, which is used, for example, by the ATP synthase to produce ATP. READ MORE