Search for dissertations about: "Structural changes"

Showing result 1 - 5 of 1007 swedish dissertations containing the words Structural changes.

  2. 1. Visualizing structural dynamics: from small molecules to membrane proteins

    Author : Magnus Andersson; [2008]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; membrane protein; bacteriorhodopsin; proteorhodopsin; halorhodopsin; structural dynamics; time-resolved X-ray scattering;

    Abstract : To fully understand the mechanism of a chemical reaction, it is important to characterize the rapid structural dynamics of transient chemical species as the reaction propagates. Since chemical processes are heavily influenced by the solvent in which they occur, the interaction with the surrounding solution also needs to be elucidated. READ MORE

  4. 2. Structural basis for metalloprotein catalysis Characterization of Mycobacterium tuberculosis phosphatidylinositol phosphate synthase PgsA1 and Bacillus anthracis ribonucleotide reductase R2

    University dissertation from Stockholm : Department of Biochemistry and Biophysics, Stockholm University

    Author : Kristīne Grāve; Martin Högbom; Susanna Törnroth-Horsefield; [2020]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; biokemi; Biochemistry;

    Abstract : About a third of all proteins need to associate with a particular metal ion or metallo-inorganic cofactor to function. This interplay expands the catalytic repertoire of enzymes and reflects the adaption of these catalytic macromolecules to the environments they have evolved in. READ MORE

  5. 3. Transthyretin and the transthyretin-related protein: A structural study

    University dissertation from Umeå : Umeå centrum för molekylär patogenes (UCMP) (Teknisk-naturvetenskaplig fakultet)

    Author : Erik Lundberg; A. Elisabeth Sauer-Eriksson; Lennart Sjölin; [2006]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Transthyretin; Transthyretin-related protein; X-ray crystallography; Protein structure; Amyloidosis; NATURAL SCIENCES Chemistry Biochemistry Structural biology; NATURVETENSKAP Kemi Biokemi Strukturbiologi;

    Abstract : Transthyretin (TTR) is one of several proteins involved in amyloid disease in humans. Unknown conformational changes of the native state of TTR result in aggregation of TTR molecules into amyloid fibrils, which accumulate in extracellular tissues. This may result in different clinical symptoms, e.g. READ MORE

  6. 4. The aged brain : structural changes and cognitive function

    University dissertation from Stockholm : Stockholm University

    Author : Hedvig Söderlund; Lena Lyons; [2003]
    Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Brain; Cognitive processes; Aging; Åldrandets psykologi; Kognitiva processer; Hjärna;

    Abstract : .... READ MORE

  7. 5. Structural Studies of Glutamine Synthetases – Towards the Development of Novel Antitubercular Agents

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Wojciech W. Krajewski; Sherry L. Mowbray; Torsten Unge; Thomas C. Terwilliger; [2008]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURAL SCIENCES Chemistry Biochemistry Structural biology; NATURVETENSKAP Kemi Biokemi Strukturbiologi;

    Abstract : Glutamine synthetase (GS) plays an important role in nitrogen metabolism, where it catalyzes the ATP-dependent condensation of glutamate and ammonia to yield glutamine. Recent studies showed the importance of M. tuberculosis GS (MtGS) for growth and survival of the bacterium, and demonstrated its potential as a drug target. READ MORE