Search for dissertations about: "Structural isomers"
Showing result 1 - 5 of 24 swedish dissertations containing the words Structural isomers.
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1. Development and application of high-throughput methods for analysis of persistent organic pollutants in human blood
Abstract : The general public is continuously exposed to a wide range of environmental pollutants. This thesis focuses on a group of anthropogenic chemicals referred to as persistent organic pollutants (POPs) that have been linked to various adverse health effects in humans. READ MORE
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2. Chemical Derivatization in Combination with Liquid Chromatography Tandem Mass Spectrometry for Detection and Structural Investigation of Glucuronides
Abstract : This thesis presents novel approaches for structural investigation of glucuronides using chemical derivatization in combination with liquid chromatography-electrospray ionization-tandem mass spectrometry (LC-ESI-MSn).Today, LC-ESI-MSn is the dominant technique for quantitative as well as qualitative analyses of metabolites, due to its high sensitivity and selectivity. READ MORE
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3. Structural and functional studies of biomolecules with NMR and CD spectroscopy
Abstract : Experimentally derived biomolecular structures were determined by Nuclear Magnetic Resonance (NMR). The properties of selected peptides and proteins in solution and in membrane mimicking micelles were observed by circular Dichroism (CD), mass spectrometry (MS), and other spectroscopic techniques. READ MORE
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4. Making Analogues of Tröger's Base – Fused oligomers, endo/exo isomers and twisted amides
Abstract : The centenarian Tröger’s base (TB) was envisaged as scaffold for the construction of tubular-shaped cleft molecules due to its the remarkable structural properties. This endeavor started with the synthesis of the three possible diastereomers of a linear symmetrically fused tris-TB analogue, the anti-anti, the syn-syn, and the syn-anti. READ MORE
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5. Methylsulphonyl-chlorobenzenes and the olfactory system : Comparative toxicity of the 2,5- and 2,6-dichlorinated isomers in mice
Abstract : Methyl sulphone metabolites of chlorinated aryl hydrocarbons are persistentenvironmental pollutants that can bioaccumulate in animals and humans. Little is known about the toxicological effects of these metabolites and this thesis is an attempt to increase this limited knowledge. READ MORE