Search for dissertations about: "Strukturbiologi"
Showing result 1 - 5 of 211 swedish dissertations containing the word Strukturbiologi.
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1. Structural studies of proteins in apoptosis and lipid signaling
Abstract : Signaling pathways control the fate of the cell. For example, they promote cell survival or commit the cell to death (apoptosis) in response to cell injury or developmental stimuli, decisions, which are vital for the proper development and functioning of metazoan. READ MORE
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2. Prediction of zinc-binding sites in proteins and efficient protein structure description and comparison
Abstract : A large number of proteins require certain metals to stabilize their structures or to function properly. About one third of all proteins in the Protein Data Bank (PDB) contain metals and it is estimated that approximately the same proportion of all proteins are metalloproteins. READ MORE
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3. Computational Analysis of Molecular Recognition Involving the Ribosome and a Voltage Gated K+ Channel
Abstract : Over the last few decades, computer simulation techniques have been established as an essential tool for understanding biochemical processes. This thesis deals mainly with the application of free energy calculations to ribosomal complexes and a cardiac ion channel. READ MORE
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4. Fighting Tuberculosis – : Structural Studies of Three Mycobacterial Proteins
Abstract : This thesis presents the cloning, purification, crystallization, and structural studies of two unknown proteins from Mycobacterium tuberculosis, and of an aminotransferase from Mycobacterium smegmatis. Structural knowledge of these proteins is of highest interest for structure-based drug design, which is one of the approaches that can be used in order to fight tuberculosis (TB). READ MORE
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5. Tunnels and Grooves : Structure-Function Studies in Two Disparate Enzymes
Abstract : This thesis describes structural and binding studies in enzymes from two different organisms: ribonucleotide reductase from Mycobacterium tuberculosis (RNR) and lipase A from Candida antarctica (CalA).RNR is viable as a target for new drugs against the causative agent of tuberculosis. READ MORE
