Search for dissertations about: "Sulfadoxine-pyrimethamine"

Showing result 1 - 5 of 9 swedish dissertations containing the word Sulfadoxine-pyrimethamine.

  1. 1. Fixed-dose chloroquine and sulfadoxine/pyrimethamine treatment of malaria : outcome and pharmacokinetic aspects

    Author : Celestino Obua; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Background: A pre-packaged fixed-dose formulation of chloroquine (CQ) and sulfadoxine/pyrimethamine (SIP) combination (Homapak) is widely used for the treatment of falciparum malaria in the Home Based Management of Fevers program for Ugandan children. Until the present study, the efficacy, pharmacokinetics and drug interactions of the dose regimen of the product were not known. READ MORE

  2. 2. Optimization of intermittent preventive therapy for malaria during pregnancy : effectiveness of dihydroartemisinin-piperaquine versus sulfadoxine-pyrimethamine

    Author : Eulambius Mathias Mlugu; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Malaria is a Tropical disease caused by different parasites species of genius Plasmodium. Because of pregnancy associated lowered immunity, women who are pregnant are at higher risk to malaria infection than non-pregnant women. READ MORE

  3. 3. Managing childhood malaria in rural Tanzania : focusing on drug use and resistance

    Author : Jaran Eriksen; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Malaria; Policy change; Sulfadoxine-pyrimethamine; Chloroquine; Tanzania; Health workers; Drug resistance;

    Abstract : Background: Malaria is a leading cause of death in underfive children in Africa. Due to the spread of chloroquine (CQ) resistance, sub-Saharan African countries such as Tanzania have changed their malaria treatment policies. In 2001 Tanzania replaced CQ with sulfadoxine/pyrimethamine (SP) as first line malaria treatment. READ MORE

  4. 4. Exploring malaria case mangement of underfive children at households and public primary health care facilities in Kibaha district, Tanzania

    Author : Stephen E D Nsimba; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Malaria; underfive children; chloroquine; sulfadoxine pyrimethamine; case management; mothers guardians; households; public health care facilities; Tanzania;

    Abstract : Background: Chloroquine (CQ) was the first line drug for treating malaria in Tanzania until 2001 when it was replaced with sulfadoxine/pyrimethamine (SP). The first four studies (I -IV) were conducted before the policy change, and the last one (V) after. READ MORE

  5. 5. Plasmodium falciparum malaria and anaemia in childhood

    Author : Håkan Ekvall; Karolinska Institutet; Karolinska Institutet; []
    Keywords : malaria; Plasmodium falciparum; haemolytic anaemia; complement; band 3 protein; chloroquine; sulfadoxine-pyrimethamine; iron; micronutrients; prospective studies; child; Tanzania;

    Abstract : Childhood anaemia represents a major health problem in sub-Saharan Africa. The anaemia is multifactorial and the result of a synergism between infectious diseases, nutritional deficiencies and inherited red cell disorders. READ MORE