Search for dissertations about: "Surface plasmon resonance SPR"

Showing result 21 - 25 of 73 swedish dissertations containing the words Surface plasmon resonance SPR.

2. 21. Characterization of biological nanoparticles using evanescent field sensing

   Author : Mattias Sjöberg; Chalmers tekniska högskola; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; label-free; protein corona; mass quantification.; liposomes; single-particle; SPR; Waveguide scattering microscopy;

   Abstract : In light of the increasingly realized importance of nanoparticle-based biological processes, in biology as well as in technological applications, there is a need of analysis methods capable of accurately quantifying different characteristics and processes involving these elusive entities. The aim of this thesis is the development and utilization of surface-based bioanalytical sensing methods for quantitative characterization of biological nanoparticles, most of which being based on surface-confined evanescent-field illumination. READ MORE

4. 22. Biosensor surface chemistry for oriented protein immobilization and biochip patterning

   Author : Emma Ericsson; Karin Enander; Sofia Svedhem; Linköpings universitet; []
   Keywords : Biochip; biosensor; hydrogel; ligand; orientation; patterning; photochemistry; protein immobilization; surface chemistry; self-assembled monolayer; SAM;

   Abstract : This licentiate thesis is focused on two methods for protein immobilization to biosensor surfaces for future applications in protein microarray formats. The common denominator is a surface chemistry based on a gold substrate with a self-assembled monolayer (SAM) of functionalized alkanethiolates. READ MORE

5. 23. Phospholipid membranes in biosensor applications : Stability, activity and kinetics of reconstituted proteins and glycolipids in supported membranes

   Author : Inga Gustafson; Gertrud Puu; Sven Lindskog; Peter Konradsson; Umeå universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; Phospholipid films; Liposomes; Membrane proteins; Glycolipids; Ellipsometry; Langmuir Blodgett LB ; Surface plasmon resonance SPR ; Resonant mirror RM ; Atomic force microscopy AFM ; Biosensors; Biokemi; Biochemistry; Biokemi; Biochemistry; biokemi;

   Abstract : In this study the formation of supported membranes onto planar solid supports has been investigated. The stability and activity of reconstituted membrane receptors has been studied. The potential use of such preparations in biosensor applications is discussed.The lipid films were made by the Langmuir Blodgett and by the liposome fusion techniques. READ MORE

6. 24. Polysaccharide thin film studies - Adsorption of oxidized xylan on cellulose

   Author : Chonnipa Palasingh; Chalmers tekniska högskola; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; surface plasmon resonance; solubility; macromolecule adsorption; quartz crystal microbalance with dissipation monitoring;

   Abstract : Wood xylans are renewable natural materials that have potential for future use in bio-based products. However, their high price and low production capacity restrict their industrial use and current applications. This research aimed to explore the potential of wood xylans for film applications. READ MORE

7. 25. Antiadhesive agents targeting uropathogenic Escherichia coli : Multivariate studies of protein-protein and protein-carbohydrate interactions

   Author : Andreas Larsson; Jan Kihlberg; Fredrik Almqvist; Mats Larhed; Umeå universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; Antibacterial; pili; antiadhesive agents; structure based design; statistical molecular design; 2-pyridone; amino acid derivative; galabiose; enaminone; SPR; ELISA; QSAR; Organisk kemi; Organic chemistry; Organisk kemi; organisk kemi; Organic Chemistry;

   Abstract : This thesis describes studies directed towards development of novel antiadhesive agents, with particular emphasis on compounds that prevent attachment of bacteria to a host-cell. Three different proteins involved in the assembly or function of adhesive pili in uropathogenic Escherichia coli have been targeted either by rational structure based design or statistical molecular methods. READ MORE