Search for dissertations about: "Surgery of pancreatic cancer"

Showing result 1 - 5 of 38 swedish dissertations containing the words Surgery of pancreatic cancer.

2. 1. Effects of Pancreatic Surgery : Quality of Life, Cost-effectiveness and Postoperative Results

   Author : Karin Johansen; Bergthor Björnsson; Per Sandström; Linda Lundgren; Jacob Freedman; Linköpings universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pancreatic surgery; Minimally invasive surgical procedures; Octogenarians; Surgical outcome; Quality of life; Cost-effectiveness analysis; Qualitative research;

   Abstract : BACKGROUND  Pancreatic operations are large procedures with high rates of complications and other potentially impactful consequences such as diabetes and pancreatic exocrine insufficiency. Due to this, and due to the fact that the operations are often occasioned by periampullary tumours with a poor prognosis, it is important to evaluate how the operations affect patients in terms of postoperative results and quality of life. READ MORE

4. 2. Translational and clinical aspects of pancreatic cancer

   Author : Caroline Vilhav; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pancreatic cancer; circulating tumor cells; extracellular vesicles; immunotherapy; PDX model; pancreaticoduodenectomy; postoperative complications; postpancreatectomy hemorrhage;

   Abstract : Pancreatic cancer is a disease with dismal prognosis due to late detection and ineffective treatments. The majority of the patients already have disseminated disease at the time of diagnosis. The only potential curative treatment, surgery, is extensive with high morbidity and non-ignorable mortality. READ MORE

5. 3. Identification of tissue biomarkers of prognostic significance in pancreatic cancer

   Author : Dingyuan Hu; Lund Kirurgi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pancreatic cancer; proteomics; mass spectrometry; Biomarkers; prognosis; CLCA1; pankreascancer; proteomik; masspektrometri; biomarkörer; prognos; CLCA1;

   Abstract : Background: Pancreatic cancer is the third leading cause of cancer-related mortality. Lack of early detection strategies and therapeutic resistance are main contributors to the poor prognosis. Unfortunately, there are no tissue biomarkers available for the prognosis of pancreatic cancer in routine clinical use. READ MORE

6. 4. Stromal components and micro-RNAs as biomarkers in pancreatic cancer

   Author : Oskar Franklin; Malin Sund; Daniel Öhlund; Ola Billing; Marco Del Chiaro; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pancreatic cancer; stroma; basement membrane; tumour markers; type IV collagen; endostatin; osteopontin; tenascin c; hyaluronan; CD44; micro-RNA; kirurgi; Surgery;

   Abstract : Background Pancreatic ductal adenocarcinoma (PDAC) patients have the poorest 5-year survival rates of all cancer forms. It is difficult to diagnose at early disease stages, tumour relapse after surgery is common, and current chemotherapies are ineffective. READ MORE

7. 5. Advances in the Perioperative Management of Pancreatic Cancer

   Author : Srinivas Sanjeevi; Christoph Ansorge; Sara Regnér; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pancreatic cancer; pancreatic ductal adenocarcinoma; prophylactic double bypass; pancreaticojejunostomy; neoadjuvant chemotherapy; post-operative pancreatic fistula; Kirurgi; Surgery;

   Abstract : Surgery is currently the only form of curative treatment for pancreatic cancer, yet five-year survival rates following resection are just 15-20%. Improved hospital care has decreased postoperative mortality to 2% yet morbidity remains high at 50%. Poor survival and high morbidity are driven by several perioperative factors. READ MORE