Search for dissertations about: "Sveinbjörn Gizurarson"
Found 2 swedish dissertations containing the words Sveinbjörn Gizurarson.
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1. Models for the Transfer of Drugs from the Nasal Cavity to the Central Nervous System
Abstract : The blood-brain barrier restricts the access of many compounds, including therapeutic agents, to the brain. Several human studies indicate that nasal administration of hydrophilic compounds, such as peptides, can bypass the blood-brain barrier. The aims of this thesis were to develop and refine models for this direct nose-to-brain transfer. READ MORE
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2. Development of a New Oral Vaccine against Diphtheria and the Study of its Immunogenicity in Mouse and Man
Abstract : Most pathogens enter the body via mucosal surfaces. In contrast to parenterally administered vaccination, mucosal vaccination has the advantage of eliciting both a systemic and a local mucosal immune response. An oral biodegradable adjuvant with these features would have great potential. READ MORE