Search for dissertations about: "Synaptic vesicle protein 2"

Showing result 1 - 5 of 17 swedish dissertations containing the words Synaptic vesicle protein 2.

2. 1. Molecular mechanisms in synaptic vesicle recycling

   Author : Joel Jakobsson; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Neurons communicate through specialized contacts called synapses, which consist of pre- and postsynaptic compartments separated by a narrow synaptic cleft. The stimulus- dependent rapid influx of calcium ions into the presynaptic compartment induces fusion of neurotransmitter-filled vesicles with the plasma membrane and release of their content into the synaptic cleft. READ MORE

4. 2. Vesicle proteins as markers for neuroendocrine tumors

   Author : Anne-Marie Levin Jakobsen; Göteborgs universitet; []
   Keywords : Neuroendocrine tumours; gastrointestinal tract; pancreas; adrenal; vesicle proteins; ; SV2; NESP55; VMAT1; VMAT2; MIBG;

   Abstract : The neuroendocrine (NE) tumours comprise a diversity of tumours which share commonproperties, e.g. the capacity to produce, store and release hormones. A prominent feature ofthe NE phenotype is the production of secretory granules with associated vescicle proteins,e. READ MORE

5. 3. Determining Ligand- and Lipid- Interactions of SLC Transporters

   Author : Yurie Chatzikyriakidou; David Drew; Robert Fredriksson; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Solute carrier transporter; nucleotide-sugar transporter; SLC35; sodium proton exchanger; SLC9B2; thermal stability assay; membrane transport; Synaptic vesicle protein 2; Biochemistry; biokemi;

   Abstract : Solute carrier transporters (SLCs) mediate the inter- and intra- cellular trafficking of a plethora of substrates and are essential to cell homeostasis. Despite their importance to human physiology and their potential as therapeutic targets, many SLCs are considered orphans as the physiological substrate has not been experimentally determined. READ MORE

6. 4. Allosteric regulation of synaptic processes

   Author : Ranjita Dutta Roy; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Glutamatergic neurotransmission is of key importance for short-term and long-term plasticity in the hippocampus, a part of the medial temporal lobe which is responsible for processes of explicit semantic and spatial memory. Short-term plasticity is mainly regulated by the presynaptic neuron and long-term plasticity is to large parts regulated by the post-synaptic neuron. READ MORE

7. 5. Coordination of endocytosis at the synaptic periactive zone

   Author : Emma Evergren; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Synapse; endocytosis; clathrin; dynamin; amphiphysin; synapsin; intersectin; actin cytoskeleton; immunogold electron microscopy.;

   Abstract : Neurons in the central nervous system communicate via specialized junctions called synapses. Neurotransmitter-filled vesicles are clustered at these junctions, where they are released in response to synaptic activity. To sustain reliable neurotransmission the synaptic vesicles are recycled locally. READ MORE