Search for dissertations about: "Synaptotagmin"

Showing result 1 - 5 of 16 swedish dissertations containing the word Synaptotagmin.

  2. 1. The Actin Filament System : Its Involvement in Cell Migration and Neurotransmitter Release

    Author : Anna-Karin Johnsson; Roger Karlsson; Stéphane Gasman; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Actin; Profilin; Synaptotagmin; Cell biology; Cellbiologi; Cell Biology; cellbiologi;

    Abstract : The microfilament system consists of actin filaments as the major component and is regulated by a number of actin binding proteins. It is juxtaposed to the plasma membrane where it forms a dense cortical weave from where it pervades into the cell interior. READ MORE

  4. 2. Exocytosis in Type 2 Diabetes- Functional and genetic studies of hormone secretion

    Author : Sofia A Andersson; Diabetes - öcellsexocytos; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 2 Diabetes; Insulin; Glucagon; Alpha-cells; Beta-cells; Exocytosis; Capacitance; SNARE; SNAP25; Syntaxin1A; Synaptotagmin; Munc-18 Stxbp1 ; SNP; Expression; miRNA;

    Abstract : Type 2 Diabetes (T2D) is characterized by dysregulated beta-and alpha-cell hormone secretion leading to elevated blood glucose levels. Several proteins are crucial in maintaining exocytosis of the hormone-containing granules such as Syntaxin1A (Stx1A), SNAP25, Munc-18 (Stxbp1) and the family of Synaptotagmins (Syts). READ MORE

  5. 3. Alzheimer's disease : towards a multifaceted approach in neuropathological diagnosis

    Author : Nenad Bogdanovic; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Alzheimer s disease; CERAD; neurofibrillary tangles. neuritic plaques; apoE. synaptic proteins; rab3a; synaptophysin; synaptotagmin; GAP-43; neurogranin; neuronal degeneration; optical disector 1998;

    Abstract : The main aim of this study has been to investigate potential neuropathological features which may play an important role in understanding the cognitive dysfunction and in making the final diagnosis of Alzheimer's disease (AD). To establish a reliable diagnosis of AD, standardisation and uniformity of the diagnostic protocols must become mandatory. READ MORE

  6. 4. Studies on proteins involved in the molecular regulation of insulin exocytosis

    Author : Wei Zhang; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Actin; ADP; ATP; Ca2 channel; CAPS; beta-cells; CSP; exocytosis; GK rat; insulin; islet; Mint; Munc-18; NSF; PI 4-kinase; PI 4 P; PI 4; 5 P2; alpha-SNAP; SNAP-25; synaptotagmin III; syntaxin; tomosyn; type 2 diabetes mellitus; VAMP-2.;

    Abstract : Type 2 diabetes mellitus is a disease characterized by impaired insulin secretion and insulin resistance. Better understanding of molecular mechanisms of insulin secretion may help to optimize type 2 diabetes management. READ MORE

  7. 5. Regulation of phagocytosis and phagolysosome fusion in human leukocytes

    Author : Maria Lindmark; Per-Arne Oldenborg; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Professional phagocytes such as neutrophil granulocytes and macrophages are an esential part of the innate immune system. The neutrophils form the first line of defence against invading microorganisms and are important for rapid killing of the intruders. READ MORE