Search for dissertations about: "Syndecan-1."
Showing result 1 - 5 of 21 swedish dissertations containing the word Syndecan-1..
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1. Syndecan-1 insights in mesothelioma
Abstract : Syndecan-1 is a cell surface heparan sulfate proteoglycan expressing on epithelial cells. Heparan sulfate (HS) chains on syndecan-1 constitute growth factor attachment sites and facilitate growth factors to bind their respective receptors. This binding property of HS chains allows syndecan-1 to be involved in various cellular processes. READ MORE
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2. Studies on syndecan-1 in mesenchymal tumors
Abstract : The syndecans are a four-member family of type I transmembrane proteoglycans. Their core proteins have a short cytoplasmic domain, a transmembrane domain and a large N-terminal extracellular domain possessing glycosaminoglycan chains. All the protein domains and the glycosaminoglycan chains can contribute to the functions of syndecans. READ MORE
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3. Human papillomavirus in recurrent respiratory papillomatosis, tonsillar and mobile tongue cancer
Abstract : This thesis focuses on the effects of the human papillomavirus (HPV) in tonsillar cancer, mobile tongue cancer, and recurrent respiratory papillomatosis (RRP). The purpose was to characterize patients with RRP in northern Sweden in order to identify more care-intensive RRP patients and to describe the voice and quality of life aspects that follow RRP. READ MORE
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4. Role of syndecan-1 in tumor cell proliferation and epithelial-mesenchymal plasticity
Abstract : Syndecan-1 (SDC1) is a heparan sulfate proteoglycan (HSPG) intercalated in the cell membrane but also translocated to the cell nucleus in a regulated manner. SDC1 is involved in several malignancy-associated processes such as proliferation and migration. READ MORE
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5. Translational studies of syndecan-1 as angiogenesis inhibitor : from basic research to clinical applications
Abstract : Malignant mesothelioma (MM) is a highly aggressive primary tumor of the pleura, associated with poor prognosis. MM is mainly related to exposure to mineral fibers such as asbestos. The diagnosis of MM, despite multiple diagnostic tools, is challenging and treatment options are limited. READ MORE