Search for dissertations about: "Systems for drug delivery applications"

Showing result 1 - 5 of 58 swedish dissertations containing the words Systems for drug delivery applications.

2. 1. Nanoparticles for multifunctional drug delivery systems

   Author : Jian Qin; Mamoun Muhammed; Paavo K J Kinnunen; KTH; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; drug delivery; stimuli-sensitive; SPION; PLLA; PNIPAAm; gold; MRI; cytotoxicity; Pluronic; phase transfer; Materials chemistry; Materialkemi;

   Abstract : Multifunctional drug delivery systems incorporated with stimuli-sensitive drug release, magnetic nanoparticles and magnetic resonance (MR) T2 contrast agents is attracting increasing attention recently. In this thesis, works on polymer nanospheres response to temperature change, superparamagnetic iron oxide nanoparticles (SPION)/polymeric composite materials for MR imaging contrast agents are summarized. READ MORE

4. 2. Ceramic Materials as Drug Delivery Systems

   Author : Amina Vazda; Håkan Engqvist; Santos Hélder; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Drug delivery; ceramics; Abuse deterrent; inhalation; single-crystals;

   Abstract : The aim of this thesis is to evaluate ceramic materials for drug delivery drugs applications. Three delivery routes were investigated; abuse-deterrent oral formulation, inhalation, and novel ceramic crystals with drug entrapped. A geopolymer matrix was developed in order to withstand non-medical abuse such as crushing, snorting, extraction etc. READ MORE

5. 3. Environment-Sensitive Multifunctional Drug Delivery Systems

   Author : Jian Qin; Mamoun Muhammed; Marcus Textor; KTH; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Materials chemistry; Materialkemi;

   Abstract : Drug delivery systems (DDS) with multiple functionalities such as environment-sensitive drug release mechanisms and visualization agents have motivated the biomedical community as well as materials chemists for more than a decade. This dissertation is concerned with the development of nanoparticles for multifunctional DDS  to tackle several crucial challenges in these complex systems, including polymeric nanospheres which respond to temperature change, superparamagnetic iron oxide nanoparticles/polymeric composite for magnetic resonance imaging contrast agents and drug carriers, immunoresponse of nanomaterials and injectable magnetic field sensitive ferrogels. READ MORE

6. 4. Mesoporous material systems for catalysis and drug delivery

   Author : Aylin Atakan; Magnus Odén; Cristina Canal; Petra de Jongh; Linköpings universitet; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

   Abstract : Hybrid material systems possess multi-functional properties which make them intriguing for the materials science community since very early dates. However, it is not straightforward to produce such material systems. A smart and efficient approach is necessary to extract the desired properties of each component under the desired conditions. READ MORE

7. 5. Lipid-based liquid crystals as drug delivery vehicles for antimicrobial peptides

   Author : Lukas Boge; Martin Andersson; Lovisa Ringstad; RISE; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Liquid crystals; liquid crystalline nanoparticles; cubosome; hexosome; phase behavior; antimicrobial peptide; AMP; glycerol monooleate; proteolysis; antimicrobial effect; antimicrobial resistance; bacterial membrane; membrane interaction; infection; topical delivery; pulmonary delivery;

   Abstract : The development of antimicrobial resistance is a great challenge within health sectors worldwide. Thus, demand for new, efficient treatments is urgent in order to treat various bacterial infections. Antimicrobial peptides (AMPs) are a group of antibiotics that have gained more and more attraction in the past decade. READ MORE