Search for dissertations about: "T cell"

Showing result 21 - 25 of 2101 swedish dissertations containing the words T cell.

  2. 21. Investigating histidine-rich glycoprotein and T cell-specific adaptor as potential biomarkers and therapeutic targets

    Author : Tor Persson Skare; Lena Claesson-Welsh; Mats Hellström; Elin Sjöberg; Jonas Fuxe; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Histidine-rich glycoprotein; T cell-specifik adaptor; Lymphoma; Glioblastoma; Vascular permeability;

    Abstract : The endothelial cell (EC), the most important cell type in blood vessels, lines the vessel wall and provides vessel integrity. EC function is tightly regulated, and its dysregulation is a key element in many diseases including cardiovascular disease, cancer and several diseases of the eye. READ MORE

  4. 22. T-Cell Protein Tyrosine Phosphatase, a Regulator of the PDGF Signaling Pathway

    Author : Susann Karlsson; Carina Hellberg; Carl-Henrik Heldin; Bengt Hallberg; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PDGF; TC-PTP; receptor trafficking; PK-M2; Medical cell biology; Medicinsk cellbiologi; molekylär cellbiologi; Molecular Cellbiology;

    Abstract : Platelet-derived growth factor (PDGF) is a potent stimulator of cell growth, survival and motility. PDGF exerts its function by binding to specific tyrosine kinase receptors, initiating receptor auotphosphorylation and initiation of specific signaling pathways that regulates the cellular response. READ MORE

  5. 23. Functional collaboration between HLH transcription factors in B cell development

    Author : Ramiro Gisler; Stamcellscentrum (SCC); []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; E47; Early B cell Factor EBF ; Clinical genetics; Klinisk genetik; HLH proteins; transcription factors; gene expression; B cell development; transcription regulation;

    Abstract : The cells in B cell development can be divided into several subgroups or fractions, e.g. early-pro-B-, pro-B, large-pre-B-, small-pre-B-, immature and mature B cells, where the stages reflect the maturity degree of the cells. READ MORE

  6. 24. Dynamic regulation of DNA methylation in human T-cell biology

    Author : Antonio Lentini; Colm Nestor; Mikael Benson; Huan Zhang; Mika Gustafsson; Ian R. Adams; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : T helper cells play a central role in orchestrating immune responses in humans. Upon encountering a foreign antigen, T helper cells are activated followed by a differentiation process where the cells are specialised to help combating the infection. READ MORE

  7. 25. Insulin promotes GABA signalling modulation in both the mouse hippocampus and human CD4+ T cells

    Author : Hayma Hammoud; Bryndis Birnir; Fredrik Elinder; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gamma-aminobutyric acid; hippocampus; tonic currents; CD4 T cells; glucose; insulin; cytokines; proliferation.; Medical Cell Biology; Medicinsk cellbiologi;

    Abstract : Gamma-aminobutyric acid (GABA) is the most common inhibitory neurotransmitter in the adult mammalian brain, where it mediates several biological functions. Rapid inhibition is predominantly mediated by the activation of GABA-A receptors that are ubiquitously expressed across the central nervous system in a cell-, circuit-, or region-specific manner. READ MORE