Search for dissertations about: "T-cell culture"
Showing result 6 - 10 of 83 swedish dissertations containing the words T-cell culture.
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6. A Study of Eosinophils – From the Human Thymus to Eosinophilic Esophagitis
Abstract : Eosinophils are cells of the innate immune system. They primarily reside within tissues and are most numerous in the gastrointestinal tract but are absent from the healthy esophagus. During the inflammatory disease eosinophilic esophagitis, eosinophils infiltrate the esophagus but their function is unknown. READ MORE
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7. Targets for immune mediated killing of tumor cells and T cell functions in B-CLL
Abstract : There is a great need for developing and improving treatment alternatives in B-cell chronic lymphocytic leukemia (B-CLL). New therapeutical approaches based on the manipulation of the immune system enable establishment of enhanced control over the malignant clone. READ MORE
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8. Monoclonal antibodies to human interferon-α and interferon-γ : Characterization and application with focus on interferon-γ as a T cell cytokine
Abstract : The major functions of the immune system are to combat infections and to control that normal auto-immunity does not turn into auto-aggression. Antibodies, together with T cell receptors and MHC molecules, dictates the immunological specificity. READ MORE
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9. Structural studies of MHC class 1 complexes : implications for NK- and T-cell recognition
Abstract : The cell-cell recognition events and the functional characteristics of the cell surface receptors that govern the responses of NK- and T-cells are central to molecular immunology. This thesis addresses the structural basis of such molecular recognition, more specifically the interaction between peptides and MHC class I molecules, as well as the interaction between such complexes and the inhibitory Ly49 receptors of NK cells or triggering antigen specific receptors of T-cells (TCR). READ MORE
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10. Recognition by and escape from CD8+ T cell immune surveillance in cancer bearing hosts
Abstract : CD8+ T cells ( TCD8+ ) can specifically recognize tumor cells through MHC class I molecules associated with peptides that are 8-l0 amino acid residues long. In recent years, a number of tumor-associated antigens, or their epitopes, have been identified and characterized with the advent of new methods in molecular biology and in peptide isolation. READ MORE
