Search for dissertations about: "T-cell"

Showing result 1 - 5 of 908 swedish dissertations containing the word T-cell.

  1. 1. Early events in T cell development

    University dissertation from Section for Immunology, Lund University

    Author : Karin Leandersson; [2002]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; pTalpha; gammadelta T cell; alphabeta T cell; development; thymus; thymocyte; serology; transplantation; Immunologi; serologi;

    Abstract : T cells constitute a heterogenous population of lymphocytes. Their unifying property is that they express surface bound antigen-receptors, called T cell receptors (TCRs). The TCR is a heterodimer composed of either TCRalpha and beta chain proteins (alphabeta TCR) or gamma and delta chain proteins (gammadelta TCR). READ MORE

  2. 2. Adoptive T Cell Therapy of Viral Infection and Cancer Ex vivo Expansion of Cytomegalovirus- and Prostate Antigen-specific T Cells

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Björn Carlsson; Uppsala universitet.; [2005]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; Immunotherapy; Adoptive T cell therapy; Dendritic cell; T cell; Tetramer; Cytomegalovirus; Transplantation; pp65; Prostate cancer; TARP; Prostate antigens; Immunologi; MEDICINE Microbiology; immunology; infectious diseases Immunology; MEDICIN Mikrobiologi; immunologi; infektionssjukdomar Immunologi;

    Abstract : The main focus of my thesis has been to develop protocols for generating antigen-specific cytotoxic T lymphocytes (CTLs) and T helper cells (TH) for adoptive transfer to treat cytomegalovirus (CMV) disease and prostate cancer. CMV viremia is a severe complication in immunocompromised stem cell transplanted patients. READ MORE

  3. 3. The MHC-glycopeptide-T cell interaction in collagen induced arthritis a study using glycopeptides, isosteres and statistical molecular design in a mouse model for rheumatoid arthritis

    University dissertation from Umeå : Kemi

    Author : Lotta Holm; Umeå universitet.; [2006]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Rheumatoid arthritis; collagen; T-cell; class II MHC; solid phase peptide synthesis; glycopeptide; peptide isostere; PCA; statistical molecular design; PLS; QSAR; sequence binding motif; NATURAL SCIENCES Chemistry Organic chemistry; NATURVETENSKAP Kemi Organisk kemi;

    Abstract : Rheumatoid arthritis (RA) is an autoimmune disease affecting approximately 1% of the population in the western world. It is characterised by a tissue specific attack of cartilage in peripheral joints. Collagen induced arthritis (CIA) is one of the most commonly used animal models for (RA), with similar symptoms and histopathology. READ MORE

  4. 4. Glucocorticoid in T cell differentiation

    University dissertation from Stockholm : Karolinska Institutet, Microbiology and Tumor Biology Center (MTC)

    Author : Yintong Xue; Karolinska Institutet.; Karolinska Institutet.; [1999]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Thymocytes differentiate into mature T cells with an immunological restriction for self major histocompatibility complex (MHC) antigens. Cells that do not recognize self MHC expressed on thymic epithelial cells (TEC) die by a rapid induction of apoptosis (default selection). READ MORE

  5. 5. Thrombospondin 1, an autocrine regulator in T cell adhesion and migration

    University dissertation from Umeå : Klinisk mikrobiologi

    Author : ShuShun Li; Umeå universitet.; [2005]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; T cell; adhesion; migration; thrombospondin; Immunologi; MEDICINE Microbiology; immunology; infectious diseases Immunology; MEDICIN Mikrobiologi; immunologi; infektionssjukdomar Immunologi; immunologi; Immunology;

    Abstract : Lymphocytes, the principal cells of the immune system, perform the immune function throughout the body by their unique capacity to circulate in blood stream and lymphatic vessels and migrate in lymphoid and non-lymphoid tissues. The mechanisms regulating lymphocyte adhesion and migration, interactions with cells and components within the extracellular matrix are not fully understood. READ MORE