Search for dissertations about: "T-cell"

Showing result 11 - 15 of 1060 swedish dissertations containing the word T-cell.

  2. 11. T-cell regulation of immune responses to the Plasmodium falciparum antigen Pf155/RESA

    Author : Lalitha Kabilan; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Antigens; surface; immunology T-lymphocytes; Plasmodium falciparum;

    Abstract : Plasmodium falciparum is the cause of the most severe malaria inhumans. Due to the rapid resurgence of malaria in many parts of theworld extensive efforts have been made during the last few years todefine several P.falciparum antigens for inclusion in a vaccine. READ MORE

  4. 12. Smoking and T cell co-stimulation in rheumatoid arthritis

    Author : Caroline Wasén; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; rheumatoid arthritis; CD8 T cell; programmed cell death-1; programmed cell death-1 ligand 1; smoking; microRNA;

    Abstract : In this thesis I investigated if smoking limits the co-stimulatory system of CD8+ T cells in rheumatoid arthritis (RA). I took special interest in the co-inhibitory receptor PD-1 and its ligand PD-L1. READ MORE

  5. 13. Epidemiological and clinical aspects of T-cell lymphoma

    Author : Henrik Cederleuf; Medicinsk onkologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; population-based; peripheral T-cell lymphoma; Anaplastic large cell lymphoma; angioimmunoblastic; elderly; ASCT; comorbidity; prognostic factors; follow-up; limited stage; etoposide; CHOP; overall survival; radiotherapy;

    Abstract : T-cell lymphoma (TCL) is a rare group of malignancies and one of the important aims in this thesis has been to broaden the general knowledge of TCL with descriptive patient data. Main focus has been to examine prognosticfactors for overall survival (OS) and progression-free survival (PFS), and to evaluate different treatment approaches and follow-up (FU) after treatment. READ MORE

  6. 14. Extrathymic T cell receptor gene rearrangement in human alimentary tract

    Author : Anna Bas; Marie-Louise Hammarström; Sten Hammarström; Adrian Hayday; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; T cell maturation; recombination activating gene; preTα; human intestinal mucosa; intraepithelial lymphocytes; lamina propria lymphocytes; nasopharyngeal tonsil; Immunologi; Immunology; Immunologi; immunologi; Immunology;

    Abstract : T lymphocytes regulate the initiation, duration, and magnitude of adaptive immune responses and function as effector cells in cell mediated immunity. To become immunologically competent they must generate functional antigen receptors. This process takes place in the thymus and requires somatic recombination of T cell receptor (TCR) genes. READ MORE

  7. 15. Towards Immunotherapy of Midgut Carcinoid Tumors

    Author : Sofia Vikman; Thomas Tötterman; Valeria Giandomenico; Bengt Widegren; Uppsala universitet; []
    Keywords : Immunology; midgut carcinoid; gene expression; immunotherapy; tumor antigen; VMAT-1; T cell; HLA-A*0201-binding peptide; IFNγ; regulatory T cell; Immunologi;

    Abstract : Classical midgut carcinoids belong to neuroendocrine tumors of the gastroenteropancreatic tract (GEP-NETs) and are associated with serotonin overproduction. The term midgut is derived from the tumors’ embryological site of origin: enterochromaffin cells in the lower jejunum, ileum, caecum and the ascending colon. READ MORE