Search for dissertations about: "T-cells"
Showing result 6 - 10 of 1140 swedish dissertations containing the word T-cells.
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6. The Multiple Faces of Genetically-Modified T Cells : Potential Applications in Therapy
Abstract : In this PhD thesis the potential of T-cells as therapy for disease are explored. The applications of genetically modified T-cells for treatment of cancer and autoimmune disease; the functionality and optimal activation of T-cells are discussed. READ MORE
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7. Generation of Therapeutic T Cells for Prostate Cancer
Abstract : The work presented herein focuses on the activation of the adaptive immune system in order to develop T cell-based immunotherapy for viral infections and cancer. The main goal was to identify and activate viral or tumoral antigen-specific T cells by using different identification, isolation and stimulation techniques. READ MORE
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8. T cells and chemokines in rheumatoid arthritis
Abstract : In this thesis, we investigated if circulating proportions of specific CD4+ T cell subsets and blood chemokine levels were associated with disease activity and/or could predict remission in patients with early rheumatoid arthritis (eRA). We also compared the effect of different biological treatments on both T cell subset proportions and chemokine levels. READ MORE
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9. Cancer Immunotherapy : Oncolytic viruses and CAR-T cells
Abstract : Various forms of cancer immunotherapy have developed rapidly with improved survival and quality of life for cancer patients. Cancer immunotherapy aims to educate the patient’s immune system to eliminate cancer cells, including immune checkpoint inhibitors (ICIs), adoptive cell transfer (mostly T cells), oncolytic viruses (OVs) and cancer vaccines. READ MORE
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10. Regulatory T cells and mucosal-associated invariant T cells in colon adenocarcinomas; Phenotype and function
Abstract : In many solid cancers, and also in colon adenocarcinomas, an increased accumulation of lymphocytes is beneficial for the patient. However, tumor-infiltrating immune cells may be either pro- or anti-tumorigenic and the balance between these two counteracting forces partly determines patient outcome. READ MORE