Search for dissertations about: "T.cruzi"

Showing result 1 - 5 of 18 swedish dissertations containing the word T.cruzi.

  2. 1. Immunobiochemical significance of Trypanosoma rangeli in the study of Trypanosoma cruzi

    Author : Azael Patiño Saldaña; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Trypanosoma rangeli is a haemoflagellate that infects humans nonpathogenically in some areas in which T. cruzi, the causative agent of Chagas' disease, is endemic. Since common biological and immunochemical characteristics have been described for these parasites, a detailed study of their relationship is needed. READ MORE

  4. 2. Experimental Chagas disease

    Author : John Andersson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Trypanosoma cruzi; NK cells; cytotoxicity; IFN-gamma; IL-12; IFN-alpha beta; Chagas disease; polymyositis; myocarditis; genotype dependence and Toll-like receptors.;

    Abstract : The main focus of this thesis was to develop and utilise experimental models using the protozoan parasite Trypanosoma cruzi. We were especially interested in studying the activation of NK cells early after T. cruzi infection and what factors that predispose to a chronic inflammatory disease after T. cruzi infection. READ MORE

  5. 3. Trypanosoma cruzi genome plasticity and evolution

    Author : Carlos Talavera-López; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Trypanosoma cruzi, a protozoan from the Kinetoplastidae family, is the etiologic agent of Chagas disease, a major public health problem affecting mostly the poorest areas of Latin America. Due to the complex nature of the parasite’s genome it has been impossible to produce a complete reference genome sequence, thus hampering the implementation of post- genomic approaches to unveil the mechanisms of generation of antigenic variation and the identification of new drug targets. READ MORE

  6. 4. Detection and characterization of novel proteins in Trypanosoma cruzi

    Author : Marcela Ferella; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Trypanosoma cruzi is a flagellated protozoan parasite. It infects a wide range of mammals, including humans. Human T. cruzi infections are endemic to South and Central America. READ MORE

  7. 5. Gene Regulation and Epigenetic Mechanisms in the Parasite Trypanosoma cruzi

    Author : Patricia Respuela; Lena Åslund; George A.M. Cross; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; Molekylärbiologi; Molecular Biology; Molekylärbiologi;

    Abstract : Trypanosomes are unicellular protozoan parasites responsible for several human diseases that affect millions of people and cause thousands of casualties every year. They also represent a primitive eukaryotic model system harboring unique processes and basic regulatory mechanisms such as RNA-editing, polycistronic transcription and trans-splicing, first described in these organisms. READ MORE