Search for dissertations about: "T3"

Showing result 6 - 10 of 71 swedish dissertations containing the word T3.

  1. 6. Life without thyroid hormone receptors

    Author : Sten Göthe; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Thyroid hormone (TH) has many important functions during development and in the adult individual. It reaches its target cells via the blood system and binds its receptor (TR) located within the cell nucleus where the receptor regulates target genes. This hormone-mediated gene regulation is a finely tuned interplay of numerous parameters. READ MORE

  2. 7. Thyroid hormones and breast cancer-prospective studies on incidence, mortality and prognostic factors

    Author : Ada Tosovic; Kirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Thyroid hormones and breast cancer-prospective studies on incidence, mortality and prognostic factors The aim of this thesis was to investigate in a prospective design, thyroid hormones in relation to breast cancer risk, mortality and prognostic factors. The association between total triiodothyronine (T3) levels and breast cancer risk was studied in 2185 women with146 incident breast cancer cases. READ MORE

  3. 8. Thyroid hormone receptors in liver metabolism

    Author : Hjalmar Gullberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Thyroid hormone has a profound impact on mammalian metabolism; hypothyroidism causes decreased metabolic rate and increased serum cholesterol levels. One major target organ for the hormone is the liver, the most important metabolic organ in mammals, that balances anabolism of carbohydrates and lipids against catabolism. READ MORE

  4. 9. More than just enduring − Mental health and well-being among Swedish young adults who ceased self-injuring since adolescence

    Author : Benjamin Claréus; Institutionen för psykologi; []
    Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; self-injury; self-harm; cessation; recovery; adolescence; well-being; mental health;

    Abstract : Non-suicidal self-injury (NSSI) is an umbrella term for non-lethal behaviours that are unlikely to be intended as suicidal, such as cutting, hitting, or burning oneself. The aims of this dissertation were to investigate i) the mental health and well-being of Swedish young adults who have ceased engaging in NSSI since adolescence, and ii) the psychosocial conditions that facilitate NSSI cessation and psychological growth during this period. READ MORE

  5. 10. Structural and functional properties of transthyretin

    Author : Anders Karlsson; A. Elisabeth Sauer-Eriksson; Salam Al-Karadaghi; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Transthyretin; Amyloidosis; X-ray crystallography; Protein structure; Protein; Structural biology; Strukturbiologi;

    Abstract : The hereditary transthyretin (TTR) amyloidoses are rare, and in severe cases, fatal disorders caused by mutations in the TTR gene. The clinical picture is diverse, involving neuropathies and myopathies, and mainly depends on the causative mutation and the sites and rates of amyloid deposition. READ MORE