Search for dissertations about: "TAD"

Showing result 11 - 15 of 18 swedish dissertations containing the word TAD.

  2. 11. T-lymphocyte mediated killing of TAP-deficient tumor cells and immunodominance of minor histocompatibility antigens

    Author : Elisabeth Z Wolpert; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Target structures and regulation of cytotoxic T lymphocyte (CTL) mediated responses is the subject of this thesis. One main finding is that cells devoid of a functional transporter associated with antigen processing (TAP) appear to express novel epitopes that can be recognized by syngenic CTL. READ MORE

  4. 12. Oxygen-dependent regulation of HIF-1alpha expression and function

    Author : Xiaowei Zheng; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Hypoxia is a state of reduced oxygen levels below normal values. It occurs in the pathophysiology of many diseases and plays important roles in mammalian physiology and development. The hypoxia-inducible factors (HIFs) are transcription factors that mediate adaptive cellular responses to hypoxia by activating the transcription of target genes. READ MORE

  5. 13. Biophysical characterization of protein-protein interactions involving intrinsically disordered proteins

    Author : Ida Nyqvist; Jakob Dogan; Ivarsson Ylva; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Intrinsically disordered proteins; Protein-protein interactions; Disorder-to-order transition; Rate-limiting transition state; Ф-value analysis; NMR relaxation; Side-chain dynamics; Backbone dynamics; Conformational entropy change; Biophysics; biofysik;

    Abstract : Intrinsically disordered proteins and regions (IDPs/Rs) are proteins that do not form stable and well-defined structures in their free states but rather occupy an ensemble of conformations that change over time while still staying functional. They are prevalent in the eukaryotic proteome and are involved in various vital processes in the cell where they often interact with their binding partners through coupled binding and folding reactions. READ MORE

  6. 14. Studies of Vacuum Dewatering on Low Grammage Paper Webs

    Author : Rickard Granevald; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Chemical Engineering; Kemiteknik;

    Abstract : A laboratory scale apparatus to simulate high-vacuum dewatering of low grammage paper sheets, typically for tissue products has been constructed. Vacuum level, vacuum pulse dwell time and frequency of single vacuum pulses are in the range typical for a Through Air Drying (TAD) tissue machine. The vacuum pulse dwell time was varied from 0. READ MORE

  7. 15. Mechanisms behind Smc5/6 transcriptional regulation and cohesin-mediated chromosome organisation

    Author : Stefina Milanova; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The eukaryotic family of Structural Maintenance of Chromosomes (SMC) complexes are multi-subunit, ring-like protein complexes and include condensin, cohesin and the Smc5/6 complex (Smc5/6). Considered as an entity, this family is essential for most chromosome-based processes, and protects against diverse human syndromes and diseases. READ MORE