Search for dissertations about: "TAF15"

Found 2 swedish dissertations containing the word TAF15.

  1. 1. Molecular analysis of the FET family fusion oncoprotein FUS-DDIT3

    Author : Christer Thomsen; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : FUS-DDIT3; FUS; EWS; TAF15; DDIT3; myxoid liposarcoma; plectin; SWI SNF;

    Abstract : Chromosomal translocations leading to formation of tumor type specific fusion oncogenes are frequently found in human cancers. The FET family genes (FUS, EWSR1 and TAF15) occur in translocations with genes encoding various transcription factors in sarcomas and leukemias. READ MORE

  2. 2. FET proteins in cancer and development

    Author : Mattias K Andersson; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : FUS; EWS; TAF15; FUS-DDIT3; myxoid liposarcoma; NF-κB; NFKBIZ; FLT1; CDK2;

    Abstract : Chromosomal translocations leading to rearrangements of FET family genes (FUS, EWSR1 and TAF15) are found in numerous human cancers. These genetic alterations result in the formation of fusion oncogenes that express potent chimeric oncoproteins able to promote tumor development. READ MORE