Search for dissertations about: "TCDD"

Showing result 21 - 25 of 35 swedish dissertations containing the word TCDD.

  2. 21. Studies on gender-specific disruption of bone tissue homeostasis by dioxins

    Author : Carolina Wejheden; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Dioxins are widespread environmental pollutants, known to cause immunosuppression, developmental and reproductive defects, as well as cancer. The toxic effects of dioxins are mediated by the aryl hydrocarbon receptor (AhR, also referred to as the dioxin receptor). READ MORE

  4. 22. Association of hydrophobic organic compounds to organic material in the soil system

    Author : Silviu-Laurentiu Badea; Mats Tysklind; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; HOCs; Organic Matter; Clay; DOM; Environmental Science; miljövetenskap;

    Abstract : Contaminated soils and sediments have been identified as significant secondary sources of organic contaminants.  Leaching tests may be useful tools to estimate the mobility of contaminants via the water phase and thereby the risk for groundwater and surface water contamination. READ MORE

  5. 23. Gender differences in chemical carcinogenesis

    Author : Sandeep Kadekar; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Gender differences in cancer incidence and mortality is a regular finding in epidemiological studies. In addition to reproductive organs this pattern is also seen in non-reproductive organs, with men being the most affected gender for the majority of cancer-sites. READ MORE

  6. 24. Computational methods for analyzing dioxin-like compounds and identifying potential aryl hydrocarbon receptor ligands : multivariate studies based on human and rodent in vitro data

    Author : Malin Larsson; Patrik Andersson; Anna Linusson; Mats Tysklind; Scott Boyer; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; dioxin-like compounds; multivariate analysis; toxic equivalency factor; quantitative structure-activity relationship; descriptors; virtual screening; in vitro; species variation; aryl hydrocarbon receptor;

    Abstract : Polychlorinated dibenzo-p-dioxins/dibenzofurans (PCDD/Fs) and polychlorinated biphenyls (PCBs) are omnipresent and persistent environmental pollutants. In particular, 29 congeners are of special concern, and these are usually referred to as dioxin-like compounds (DLCs). READ MORE

  7. 25. Comparative studies of alkylating and N-heterocyclic compounds on different genetic endpoints with special emphasis on amplification of minisatellite sequences

    Author : Eva Agurell; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : Several mutational events are involved in the multistage process of cancer. Genetic instability of tumor DNA is shown in a variety of genetic changes such as point mutations, chromosomal aberrations, aneuploidy, DNA amplification and somatic recombination. READ MORE