Search for dissertations about: "TCF7L2"
Showing result 11 - 15 of 26 swedish dissertations containing the word TCF7L2.
-
11. Diabetes mellitus and risk of prostate cancer - A focus on shared risk factors and survivor bias
Abstract : Prostate cancer (PCa) is a heterogenous disease including very aggressive lethal tumors to incidentally discovered clinically insignificant tumors. Age, ethnicity, and family history are the only established risk factors. READ MORE
-
12. Identification of susceptibility genes in type 2 diabetes
Abstract : Identification of the susceptibility genes will offer better understanding of molecular mechanisms underlying T2D pathogenesis, and subsequently may lead to development of novel therapeutic approaches. This thesis mainly concerns the genetic association study of four candidate genes. READ MORE
-
13. Degradomics : a study of the cellular proteolytic landscape in enterovirus infections
Abstract : The common human pathogen, enteroviruses (EVs) are a genus of single stranded RNA viruses that include Coxsackie B virus (CVBs). The viral RNA encodes a polyprotein containing two viral proteases 2Apro and 3Cpro, that process the polyprotein into structural and non-structural proteins during virus replication. READ MORE
-
14. Roles of voltage-gated Ca2+ channel subunits in pancreatic β cells
Abstract : Hallmarks of type 2 diabetes (T2D) include elevated blood glucose and free fatty acids (FFAs) as a result of impaired β cell insulin secretion and decreased β cell mass. The glucose-stimulated insulin secretion (GSIS) in β cells is triggered by depolarization-evoked Ca2+ entry through voltage-gated Ca2+ (CaV) channels. READ MORE
-
15. The impact of ethnicity on type 2 diabetes
Abstract : Abstract Type 2 diabetes mellitus is among the fastest growing diseases in the world. The reported prevalence of T2D appears to differ among various ethnic groups. READ MORE