Search for dissertations about: "TEL"

Showing result 11 - 15 of 25 swedish dissertations containing the word TEL.

  2. 11. Paracrine and autocrine functions of PDGF in malignant disease

    Author : Tobias Sjöblom; Lars Holmgren; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; Cellbiologi; Cell biology; Cellbiologi; Molecular Biology; molekylärbiologi;

    Abstract : Growth factors and their receptors are frequently activated by mutations in human cancer. Platelet-derived growth factor (PDGF)-B and its tyrosine kinase receptor, the PDGF β-receptor, have been implicated in autocrine transformation as well as paracrine stimulation of tumor growth. READ MORE

  4. 12. Studies on ITK-SYK signaling pathways

    Author : Alamdar Hussain; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Chromosomal alterations are frequent causes of cancer. Until now, SYK is reported in two different chromosomal translocation events generating the ITK-SYK-fusion protein in a subset of peripheral T cell lymphomas and the TEL-SYK fusion protein in a case of myelodysplastic syndrome. READ MORE

  5. 13. Upper Secondary Teachers as Designers of Technology Use for Learning

    Author : Elisabeth Rolf; Robert Ramberg; Ola Knutsson; Åke Walldius; Stockholms universitet; []
    Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Design patterns; design for learning; digital competence; pedagogy; technology in education; Computer and Systems Sciences; data- och systemvetenskap;

    Abstract : The use of technology in education is by policymakers expected to expand, and efforts are laid out by the research community to support such a development. This thesis will explore how the introduction of design patterns in upper secondary education may contribute to an extended use of technology by applying the Educational Design Research (EDR) methodology. READ MORE

  6. 14. Mechanisms of unreduced gamete formation in Arabidopsis thaliana

    Author : Jun Yi; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : Polyploidy is a widespread phenomenon in plants, which is commonly believed to arise through the production of unreduced (2n) gametes due to meiotic failure. Despite the importance of unreduced gamete formation for plant polyploidization, the mechanisms leading to their formation are not well understood. READ MORE

  7. 15. Characterisation of chromosomal aberrations in childhood leukaemia

    Author : Ann Nordgren; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Chromosome aberrations; SKY; interphase-FISH; Childhood ALL;

    Abstract : Acute lymphoblastic leukaemia (ALL) is the most common malignancy in childhood, accounting for approximately 25% of all paediatric malignancies. Based on clinical risk criteria and modem laboratory investigations including immunophenotyping, cytogenetics, and molecular genetics, patients can be divided into prognostic groups and assigned to risk- adjusted treatment protocols. READ MORE