Search for dissertations about: "TGF-alpha"
Showing result 1 - 5 of 7 swedish dissertations containing the word TGF-alpha.
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1. Studies of transforming growth factor alpha in normal and abnormal growth
Abstract : Regulation of growth is of fundamental importance for development of the organism and to maintain health. The induction of cell proliferation and matrix production are influenced by several different signaling systems, most importantly by growth factors. READ MORE
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2. Notch Signaling in Human Neuroblastoma Cells
Abstract : Neuroblastoma is a childhood tumor derived from the sympathetic nervous system (SNS). It is believed that the tumors arise from cells halted in their differentiation and due to their immature phenotype; they express proteins normally only detected during embryogenesis. One such protein is Hash-1, which is required for formation of the SNS. READ MORE
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3. Gene expression in the dorsal root ganglion and the role of PAI-1 and amphiregulin during regeneration
Abstract : This thesis is concerned with two aspects of peripheral nerve injury. First the early changes in the gene expression of the dorsal root ganglion (DRG) in response to sciatic nerve injury as revealed by micro-array analysis. Second an examination of the effect of PAI-1 and amphiregulin on survival and axonal outgrowth from DRG. READ MORE
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4. Paracrine regulation of Sertoli cell proliferation
Abstract : The Sertoli cell is a highly differentiated somatic cell in the seminiferous epithelium of the testis. This cell is of prime importance for both testicular development and spermatogenesis. READ MORE
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5. Matrix metalloproteases and cell motility in malignant mesothelioma
Abstract : Invasion and metastasis of malignant tumor cells requires destruction of and migration through extracellular matrix (ECM) such as basement membrane and interstitial stroma. The ECM-degrading proteases produced by tumor cells and stromal cells and cell motility play a crucial role in this process. READ MORE