Search for dissertations about: "TGF-beta and pi3k pathway"

Found 2 swedish dissertations containing the words TGF-beta and pi3k pathway.

  2. 1. Mechanisms for TGF-β-Mediated Regulation of the Actin Filament System and Apoptosis

    Author : Sofia Edlund; Pontus Aspenström; Maréne Landström; Tommy Andersson; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; TGF-beta; cytoskeleton; GTPases; mitogen-activated protein kinase kinase 3; TGF-beta-activated kinase 1; Apoptosis; Smad7; beta-catenin; p38 MAPK; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi; molekylär cellbiologi; Molecular Cellbiology;

    Abstract : Transforming growth factor-β (TGF-β) is a member of a large superfamily of cytokines which participate in many different types of cellular processes, such as growth inhibition, cell migration, differentiation, cell adhesion, wound healing and immunosuppression. Alterations of TGF-β superfamily signalling results in several different disorders, including bone disease, vascular disease and cancer. READ MORE

  4. 2. TGF-beta signaling in carcinogenic transformation of breast epithelial cells, using proteomics

    Author : Nimesh Bhaskaran; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Transforming growth factor-beta (TGFbeta) is a key regulator of cell proliferation, death, migration and differentiation. One of the features of TGFbeta signaling is to inhibit tumor growth at the early stage of cancer but promotes tumorigenesis at the advanced stage. READ MORE