Search for dissertations about: "THESIS ON dose"

Showing result 1 - 5 of 2018 swedish dissertations containing the words THESIS ON dose.

2. 1. Dose Adaptation Based on Pharmacometric Models

   Author : Johan Wallin; Mats Karlsson; Lena Friberg; Maria Garrido; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biopharmacy; Biofarmaci; Pharmacokinetics and Drug Therapy; Farmakokinetik och läkemedelsterapi;

   Abstract : Many drugs exhibit major variability in both pharmacokinetic (PK) and pharmacodynamic (PD) parameters that prevents the use of the same dose for all patients. Variability can occur both between patients (IIV) as well as within patients over the course of time (IOV). READ MORE

4. 2. Evaluation of absorbed dose and image quality in mammography

   Author : Bengt Hemdal; Malmö Medicinsk strålningsfysik; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; optically stimulated luminescence; radioluminescence; in vivo dosimetry; dose reduction; dose protocol; average glandular dose; absorbed dose; Breast cancer; mammography; Monte Carlo; image quality; image quality criteria; contrast-detail phantom;

   Abstract : Mammography refers to the X-ray examination of the human breast, and is considered the single most important diagnostic tool in the early detection of breast cancer, which is by far the most common cancer among women. There is good evidence from clinical trials, that mammographic screening can reduce the breast cancer mortality with about 30%. READ MORE

5. 3. Biomarkers of ionising radiation relevant to carcinogenesis : Dose, dose rate and LET dependency of the responses

   Author : Milagrosa López Riego; Andrzej Wojcik; Lovisa Lundholm; Alexandros G. Georgakilas; Stockholms universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Ionising radiation; low dose; low dose rate; linear energy transfer LET ; mixed beams; dose and dose rate effectiveness factor DDREF ; cancer; DNA damage response; biomarkers; molekylär biovetenskap; Molecular Bioscience;

   Abstract : A better understanding of the relationship between ionising radiation (IR) dose, dose rate and radiation quality, and the risk of stochastic effects would improve risk extrapolation from atomic bomb survivors’ data. Owing to insufficient statistical power of epidemiological studies to detect excess incidence of cancer following low doses of IR delivered at low dose rates (LDLDR), as typically encountered in most common human exposure scenarios, radiobiological experiments are fundamental to describe the biological effectiveness of LDLDR and to define the underlying molecular mechanisms. READ MORE

6. 4. Probabilistic treatment planning based on dose coverage : How to quantify and minimize the effects of geometric uncertainties in radiotherapy

   Author : David Tilly; Anders Ahnesjö; Erik Grusell; Uwe Oelfke; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Radiotherapy; treatment simulation; probabilistic planning; dose calculation; probabilistic optimization; statistical shape model; Medicinsk radiofysik; Medical Radiophysics;

   Abstract : Traditionally, uncertainties are handled by expanding the irradiated volume to ensure target dose coverage to a certain probability. The uncertainties arise from e.g. the uncertainty in positioning of the patient at every fraction, organ motion and in defining the region of interests on the acquired images. READ MORE

7. 5. On the use of radiography and radiation dose consideration in orthodontic treatment

   Author : Christina Stervik; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; effective dose; errors; estimated risk; intra-oral radiograph; organ dose; orthodontic treatment; orthodontists; panoramic image; questionnaires; radiation doses;

   Abstract : The aims of this thesis were to analyse the use of radiography and radiation risk associated with orthodontic treatment. Study I measured absorbed doses to radiosensitive organs in the head and neck in an anthropomorphic phantom head using thermo¬luminescent dosimeters (TLDs) from digital intra-oral and panoramic radiography. READ MORE